Methodology of stable peptide based on propargylated sulfonium

Methodology of stable peptide based on propargylated sulfonium

Peptides can be used as effective molecular tool for covalent modification of proteins and play important roles in ligand directed covalent modification. Tyr-selective protein modifications exert a profound impact on protein functionality. Here, we developed a general strategy that involves nucleoph...

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Bibliographic Details
Main Authors: Heng Li, Zhanfeng Hou, Yuena Wang, Ziyuan Zhou, Jin Cai, Qilei Xin, Feng Yin, Zigang Li, Naihan Xu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Sulfonium
Tyrosine modification
Staple peptide
Labeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823000894

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