Early Diagnostics of Vulvar Intraepithelial Neoplasia
The spectrum of vulvar lesions ranges from infective and benign dermatologic conditions to vulvar precancer and invasive cancer. Distinction based on the characteristics of vulvar lesions is often not indicative of histology. Vulvoscopy is a useful tool in the examination of vulvar pathology. It is...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/7/1822 |
| _version_ | 1797440075159568384 |
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| author | Vesna Kesić Pedro Vieira-Baptista Colleen K. Stockdale |
| author_facet | Vesna Kesić Pedro Vieira-Baptista Colleen K. Stockdale |
| author_sort | Vesna Kesić |
| collection | DOAJ |
| description | The spectrum of vulvar lesions ranges from infective and benign dermatologic conditions to vulvar precancer and invasive cancer. Distinction based on the characteristics of vulvar lesions is often not indicative of histology. Vulvoscopy is a useful tool in the examination of vulvar pathology. It is more complex than just colposcopic examination and presumes naked eye examination accompanied by magnification, when needed. Magnification can be achieved using a magnifying glass or a colposcope and may aid the evaluation when a premalignant or malignant lesion is suspected. It is a useful tool to establish the best location for biopsies, to plan excision, and to evaluate the entire lower genital system. Combining features of vulvar lesions can help prediction of its histological nature. Clinically, there are two distinct premalignant types of vulvar intraepithelial neoplasia: HPV-related VIN, more common in young women, multifocal and multicentric; VIN associated with vulvar dermatoses, more common in older women and usually unicentric. For definite diagnosis, a biopsy is required. In practice, the decision to perform a biopsy is often delayed due to a lack of symptoms at the early stages of the neoplastic disease. Clinical evaluation of all VIN lesions should be conducted very carefully, because an underlying early invasive squamous cancer may be present. |
| first_indexed | 2024-03-09T12:01:50Z |
| format | Article |
| id | doaj.art-937b5908e4824114875bdfb0020a13d6 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T12:01:50Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-937b5908e4824114875bdfb0020a13d62023-11-30T23:02:32ZengMDPI AGCancers2072-66942022-04-01147182210.3390/cancers14071822Early Diagnostics of Vulvar Intraepithelial NeoplasiaVesna Kesić0Pedro Vieira-Baptista1Colleen K. Stockdale2Medical Faculty, University of Belgrade, 11000 Belgrade, SerbiaLower Genital Tract Unit, Centro Hospitalar de São João, 4200-319 Porto, PortugalDepartment of Obstetrics & Gynecology, Vulvar Vaginal Disease and Colposcopy Clinics, University Iowa Healthcare, Iowa City, IA 52242, USAThe spectrum of vulvar lesions ranges from infective and benign dermatologic conditions to vulvar precancer and invasive cancer. Distinction based on the characteristics of vulvar lesions is often not indicative of histology. Vulvoscopy is a useful tool in the examination of vulvar pathology. It is more complex than just colposcopic examination and presumes naked eye examination accompanied by magnification, when needed. Magnification can be achieved using a magnifying glass or a colposcope and may aid the evaluation when a premalignant or malignant lesion is suspected. It is a useful tool to establish the best location for biopsies, to plan excision, and to evaluate the entire lower genital system. Combining features of vulvar lesions can help prediction of its histological nature. Clinically, there are two distinct premalignant types of vulvar intraepithelial neoplasia: HPV-related VIN, more common in young women, multifocal and multicentric; VIN associated with vulvar dermatoses, more common in older women and usually unicentric. For definite diagnosis, a biopsy is required. In practice, the decision to perform a biopsy is often delayed due to a lack of symptoms at the early stages of the neoplastic disease. Clinical evaluation of all VIN lesions should be conducted very carefully, because an underlying early invasive squamous cancer may be present.https://www.mdpi.com/2072-6694/14/7/1822vulvaprecancerdiagnosticsvulvoscopy |
| spellingShingle | Vesna Kesić Pedro Vieira-Baptista Colleen K. Stockdale Early Diagnostics of Vulvar Intraepithelial Neoplasia Cancers vulva precancer diagnostics vulvoscopy |
| title | Early Diagnostics of Vulvar Intraepithelial Neoplasia |
| title_full | Early Diagnostics of Vulvar Intraepithelial Neoplasia |
| title_fullStr | Early Diagnostics of Vulvar Intraepithelial Neoplasia |
| title_full_unstemmed | Early Diagnostics of Vulvar Intraepithelial Neoplasia |
| title_short | Early Diagnostics of Vulvar Intraepithelial Neoplasia |
| title_sort | early diagnostics of vulvar intraepithelial neoplasia |
| topic | vulva precancer diagnostics vulvoscopy |
| url | https://www.mdpi.com/2072-6694/14/7/1822 |
| work_keys_str_mv | AT vesnakesic earlydiagnosticsofvulvarintraepithelialneoplasia AT pedrovieirabaptista earlydiagnosticsofvulvarintraepithelialneoplasia AT colleenkstockdale earlydiagnosticsofvulvarintraepithelialneoplasia |