Conformational flexibility in neutralization of SARS-CoV-2 by naturally elicited anti-SARS-CoV-2 antibodies
The neutralization of SARS-CoV-2 and variants of concern by nine monoclonal antibodies (mAb) isolated from convalescent donors infected with the Wuhan-Hu-1 strain alongside structural characterization of two of the mAbs in complex with the RBD and spike are presented.
Bibliographic Details
Main Authors: |
Ruofan Li,
Michael Mor,
Bingting Ma,
Alex E. Clark,
Joel Alter,
Michal Werbner,
Jamie Casey Lee,
Sandra L. Leibel,
Aaron F. Carlin,
Moshe Dessau,
Meital Gal-Tanamy,
Ben A. Croker,
Ye Xiang,
Natalia T. Freund |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2022-08-01
|
Series: | Communications Biology
|
Online Access: | https://doi.org/10.1038/s42003-022-03739-5
|