Determination of Human Papiloma and Herpes Simplex Viruses and Their Possible Relation to the Presence and Type of Preinvasive Lesions on the Uterine Cervix
Cervical cancer persists as a public health problem worldwide. Among the most studied infectious agents that have been associated with neoplasic processes are viruses, including herpes and papilloma. This research was carried out in or der to determine the possible relation between infection with he...
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| Format: | Article |
| Language: | English |
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Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
2013-10-01
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| Series: | Kasmera |
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| Online Access: | https://produccioncientificaluz.org/index.php/kasmera/article/view/8448 |
| _version_ | 1797723136632815616 |
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| author | Ricardo Atencio Angela Bracho Leticia Porto Jennifer Gotera Natacha Pirela Diana Callejas Sergio Osorio María Atencio |
| author_facet | Ricardo Atencio Angela Bracho Leticia Porto Jennifer Gotera Natacha Pirela Diana Callejas Sergio Osorio María Atencio |
| author_sort | Ricardo Atencio |
| collection | DOAJ |
| description | Cervical cancer persists as a public health problem worldwide. Among the most studied infectious agents that have been associated with neoplasic processes are viruses, including herpes and papilloma. This research was carried out in or der to determine the possible relation between infection with herpes simplex virus (HSV) and human papilloma virus (HPV) and the presence and type of pre-invasive cervical lesions. Sixty-five samples of cervical tissue with lesions and ten apparently healthy controls were selected from female patients for the detection of HSV and HPV. PCR and hybridization HC2) methods were implemented for genotyping HPV. For HPV, 15.38% were positive while for HSV, 20.0%. There was one case of co-infection in a patient with a high grade intra epithelial lesion (HSIL), showing a significant difference be tween HPV-positive patients with HSIL compared to women with LSIL, low grade intraepithelial lesions. Most of the HSV positive cases were detected in patients with LSIL. A significant correlation was proved between the type of lesion and the presence of high and low risk HPV genotypes. |
| first_indexed | 2024-03-12T09:58:34Z |
| format | Article |
| id | doaj.art-937d507626f146a3b6f3ab522d8bf36c |
| institution | Directory Open Access Journal |
| issn | 0075-5222 2477-9628 |
| language | English |
| last_indexed | 2024-03-12T09:58:34Z |
| publishDate | 2013-10-01 |
| publisher | Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales |
| record_format | Article |
| series | Kasmera |
| spelling | doaj.art-937d507626f146a3b6f3ab522d8bf36c2023-09-02T11:58:52ZengUniversidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y TropicalesKasmera0075-52222477-96282013-10-014121451538448Determination of Human Papiloma and Herpes Simplex Viruses and Their Possible Relation to the Presence and Type of Preinvasive Lesions on the Uterine CervixRicardo Atencio0Angela Bracho1Leticia Porto2Jennifer Gotera3Natacha Pirela4Diana Callejas5Sergio Osorio6María Atencio7Laboratorio Regional de Referencia Virológica. Escuela de Bioanálisis. Universidad del Zulia.Escuela de Bioanálisis. Universidad del Zulia.Laboratorio Regional de Referencia Virológica. Escuela de Bioanálisis. Universidad del Zulia.Laboratorio Regional de Salud Pública del estado Zulia.Escuela de Bioanálisis. Facultad de Medicina. Universidad del ZuliaEscuela de Bioanálisis. Universidad del Zulia.Escuela de Medicina. Facultad de Medicina. Universidad del ZuliaEscuela de Medicina. Facultad de Medicina. Universidad del ZuliaCervical cancer persists as a public health problem worldwide. Among the most studied infectious agents that have been associated with neoplasic processes are viruses, including herpes and papilloma. This research was carried out in or der to determine the possible relation between infection with herpes simplex virus (HSV) and human papilloma virus (HPV) and the presence and type of pre-invasive cervical lesions. Sixty-five samples of cervical tissue with lesions and ten apparently healthy controls were selected from female patients for the detection of HSV and HPV. PCR and hybridization HC2) methods were implemented for genotyping HPV. For HPV, 15.38% were positive while for HSV, 20.0%. There was one case of co-infection in a patient with a high grade intra epithelial lesion (HSIL), showing a significant difference be tween HPV-positive patients with HSIL compared to women with LSIL, low grade intraepithelial lesions. Most of the HSV positive cases were detected in patients with LSIL. A significant correlation was proved between the type of lesion and the presence of high and low risk HPV genotypes.https://produccioncientificaluz.org/index.php/kasmera/article/view/8448Virus Papiloma Humano, Virus Herpes Simple, Cáncer de Cuello Uterino |
| spellingShingle | Ricardo Atencio Angela Bracho Leticia Porto Jennifer Gotera Natacha Pirela Diana Callejas Sergio Osorio María Atencio Determination of Human Papiloma and Herpes Simplex Viruses and Their Possible Relation to the Presence and Type of Preinvasive Lesions on the Uterine Cervix Kasmera Virus Papiloma Humano, Virus Herpes Simple, Cáncer de Cuello Uterino |
| title | Determination of Human Papiloma and Herpes Simplex Viruses and Their Possible Relation to the Presence and Type of Preinvasive Lesions on the Uterine Cervix |
| title_full | Determination of Human Papiloma and Herpes Simplex Viruses and Their Possible Relation to the Presence and Type of Preinvasive Lesions on the Uterine Cervix |
| title_fullStr | Determination of Human Papiloma and Herpes Simplex Viruses and Their Possible Relation to the Presence and Type of Preinvasive Lesions on the Uterine Cervix |
| title_full_unstemmed | Determination of Human Papiloma and Herpes Simplex Viruses and Their Possible Relation to the Presence and Type of Preinvasive Lesions on the Uterine Cervix |
| title_short | Determination of Human Papiloma and Herpes Simplex Viruses and Their Possible Relation to the Presence and Type of Preinvasive Lesions on the Uterine Cervix |
| title_sort | determination of human papiloma and herpes simplex viruses and their possible relation to the presence and type of preinvasive lesions on the uterine cervix |
| topic | Virus Papiloma Humano, Virus Herpes Simple, Cáncer de Cuello Uterino |
| url | https://produccioncientificaluz.org/index.php/kasmera/article/view/8448 |
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