Characterization of mitochondrial iron uptake in HepG2 cells

Characterization of mitochondrial iron uptake in HepG2 cells

There is increasing evidence that accumulation of redox-active iron in mitochondria leads to oxidative damage and contributes to various neurodegenerative diseases, such as Friedreich's ataxia and Parkinson's disease. In this work, we examined the existence of regulatory mechanisms for mit...

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Bibliographic Details
Main Authors: DORA INÉS MAZARIEGOS, Z. IOAV CABANTCHIK, BRUCE K CASSELS, MARCO TULIO NÚÑEZ
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Biological Research
Subjects:
mitochondria
iron homeostasis
RPA
HepG2 cells
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000100024

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