Using parental phenotypes in case-parent studies
In studies of case-parent triads, information is often collected about history of the condition in the parents, but typically parental phenotypes are ignored. Including that information in analyses may increase power to detect genetic association for autosomal variants. Our proposed approach uses pa...
Main Authors: | Min eShi, David eUmbach, Clarice eWeinberg |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-06-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00221/full |
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