CD4+CD25+FOXP3+ regulatory T cells: a potential “armor” to shield “transplanted allografts” in the war against ischemia reperfusion injury
Despite the advances in therapeutic interventions, solid organ transplantation (SOT) remains the “gold standard” treatment for patients with end-stage organ failure. Recently, vascularized composite allotransplantation (VCA) has reemerged as a feasible treatment option for patients with complex comp...
Main Authors: | Shareni Jeyamogan, Joseph R. Leventhal, James M. Mathew, Zheng Jenny Zhang |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-10-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1270300/full |
Similar Items
-
Foxp3+ regulatory T cell therapy for tolerance in autoimmunity and solid organ transplantation
by: Jes M. Sanders, et al.
Published: (2022-11-01) -
Identification of cuproptosis-related biomarkers and analysis of immune infiltration in allograft lung ischemia-reperfusion injury
by: Jianying Qin, et al.
Published: (2023-11-01) -
Shikonin Prolongs Allograft Survival via Induction of CD4+FoxP3+ Regulatory T Cells
by: Qiaohuang Zeng, et al.
Published: (2019-04-01) -
Requirement of cognate CD4+ T-cell recognition for the regulation of allospecific CTL by human CD4+ CD127- CD25+ FOXP3+ cells generated in MLR.
by: Yuming Yu, et al.
Published: (2011-01-01) -
A New Immunosuppressive Molecule Emodin Induces both CD4+FoxP3+ and CD8+CD122+ Regulatory T Cells and Suppresses Murine Allograft Rejection
by: Feifei Qiu, et al.
Published: (2017-11-01)