Critical success factors for high routine immunisation performance: a qualitative analysis of interviews and focus groups from Nepal, Senegal, and Zambia

Objectives Vaccination averts an estimated 2–3 million deaths annually. Although vaccine coverage improvements across Africa and South Asia have remained below global targets, several countries have outperformed their peers with significant increases in coverage. The objective of this study was to e...

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Main Authors: William Kilembe, Matthew C Freeman, Anna Ellis, Robert Bednarczyk, Zoe Sakas, Moussa Sarr, Kyra A Hester, Sameer Dixit, Emily A Ogutu, Katie Rodriguez
Format: Article
Language:English
Published: BMJ Publishing Group 2023-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/10/e070541.full
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author William Kilembe
Matthew C Freeman
Anna Ellis
Robert Bednarczyk
Zoe Sakas
Moussa Sarr
Kyra A Hester
Sameer Dixit
Emily A Ogutu
Katie Rodriguez
author_facet William Kilembe
Matthew C Freeman
Anna Ellis
Robert Bednarczyk
Zoe Sakas
Moussa Sarr
Kyra A Hester
Sameer Dixit
Emily A Ogutu
Katie Rodriguez
author_sort William Kilembe
collection DOAJ
description Objectives Vaccination averts an estimated 2–3 million deaths annually. Although vaccine coverage improvements across Africa and South Asia have remained below global targets, several countries have outperformed their peers with significant increases in coverage. The objective of this study was to examine these countries’ vaccination programmes and to identify and describe critical success factors that may have supported these improvements.Design Multiple case study design using qualitative research methods.Setting Three countries with high routine immunisation rates: Nepal, Senegal, and Zambia.Participants We conducted 207 key informant interviews and 71 focus group discussions with a total of 678 participants. Participants were recruited from all levels, including government officials, health facility staff, frontline workers, community health workers, and parents. Participants were recruited from both urban and rural districts in Nepal, Senegal, and Zambia.Results Our data revealed that the critical success factors for vaccination programmes relied on the cultural, historical, and statutory context in which the interventions were delivered. In Nepal, Senegal, and Zambia, high immunisation coverage was driven by (1) strong governance structures and healthy policy environments; (2) adjacent successes in health system strengthening; (3) government-led community engagement initiatives, and (4) adaptation considering contextual factors at all levels of the health system.Conclusions Throughout this project, our analysis returned to the importance of defining and understanding the context, governance, financing, and health systems within a country, rather than focusing on any one intervention. This paper augments findings from existing literature by highlighting how contextual factors impact implementation decisions that have led to improvements in childhood vaccine delivery. Findings from this research may help identify transferable lessons and support actionable recommendations to improve national immunisation coverage in other settings.
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spelling doaj.art-9381298f8dbc44e3af36ff7c8cf4580a2023-11-07T13:45:08ZengBMJ Publishing GroupBMJ Open2044-60552023-10-01131010.1136/bmjopen-2022-070541Critical success factors for high routine immunisation performance: a qualitative analysis of interviews and focus groups from Nepal, Senegal, and ZambiaWilliam Kilembe0Matthew C Freeman1Anna Ellis2Robert Bednarczyk3Zoe Sakas4Moussa Sarr5Kyra A Hester6Sameer Dixit7Emily A Ogutu8Katie Rodriguez9Rwanda Zambia HIV Research Group, Emory University, Lusaka, ZambiaGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USAGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USAGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USAGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USAInstitut de Recherche en Santé de Surveillance Epidemiologique et de Formation, Dakar, SenegalGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USACenter for Molecular Dynamics Nepal, Kathmandu, NepalGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USAGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USAObjectives Vaccination averts an estimated 2–3 million deaths annually. Although vaccine coverage improvements across Africa and South Asia have remained below global targets, several countries have outperformed their peers with significant increases in coverage. The objective of this study was to examine these countries’ vaccination programmes and to identify and describe critical success factors that may have supported these improvements.Design Multiple case study design using qualitative research methods.Setting Three countries with high routine immunisation rates: Nepal, Senegal, and Zambia.Participants We conducted 207 key informant interviews and 71 focus group discussions with a total of 678 participants. Participants were recruited from all levels, including government officials, health facility staff, frontline workers, community health workers, and parents. Participants were recruited from both urban and rural districts in Nepal, Senegal, and Zambia.Results Our data revealed that the critical success factors for vaccination programmes relied on the cultural, historical, and statutory context in which the interventions were delivered. In Nepal, Senegal, and Zambia, high immunisation coverage was driven by (1) strong governance structures and healthy policy environments; (2) adjacent successes in health system strengthening; (3) government-led community engagement initiatives, and (4) adaptation considering contextual factors at all levels of the health system.Conclusions Throughout this project, our analysis returned to the importance of defining and understanding the context, governance, financing, and health systems within a country, rather than focusing on any one intervention. This paper augments findings from existing literature by highlighting how contextual factors impact implementation decisions that have led to improvements in childhood vaccine delivery. Findings from this research may help identify transferable lessons and support actionable recommendations to improve national immunisation coverage in other settings.https://bmjopen.bmj.com/content/13/10/e070541.full
spellingShingle William Kilembe
Matthew C Freeman
Anna Ellis
Robert Bednarczyk
Zoe Sakas
Moussa Sarr
Kyra A Hester
Sameer Dixit
Emily A Ogutu
Katie Rodriguez
Critical success factors for high routine immunisation performance: a qualitative analysis of interviews and focus groups from Nepal, Senegal, and Zambia
BMJ Open
title Critical success factors for high routine immunisation performance: a qualitative analysis of interviews and focus groups from Nepal, Senegal, and Zambia
title_full Critical success factors for high routine immunisation performance: a qualitative analysis of interviews and focus groups from Nepal, Senegal, and Zambia
title_fullStr Critical success factors for high routine immunisation performance: a qualitative analysis of interviews and focus groups from Nepal, Senegal, and Zambia
title_full_unstemmed Critical success factors for high routine immunisation performance: a qualitative analysis of interviews and focus groups from Nepal, Senegal, and Zambia
title_short Critical success factors for high routine immunisation performance: a qualitative analysis of interviews and focus groups from Nepal, Senegal, and Zambia
title_sort critical success factors for high routine immunisation performance a qualitative analysis of interviews and focus groups from nepal senegal and zambia
url https://bmjopen.bmj.com/content/13/10/e070541.full
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