Ambulatory Blood Pressure Monitoring as a Useful Tool in the Cardiological Assessment of Pancreas Transplant Recipients with Type 1 Diabetes
Having the appropriate tools to identify pancreas recipients most susceptible to coronary artery disease (CAD) is crucial for pretransplant cardiological assessment. The aim of this study is to evaluate the association between blood pressure (BP) indices provided by ambulatory blood pressure monitor...
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MDPI AG
2023-08-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/17/2724 |
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| author | Małgorzata Buksińska-Lisik Przemysław Jerzy Kwasiborski Robert Ryczek Wojciech Lisik Artur Mamcarz |
| author_facet | Małgorzata Buksińska-Lisik Przemysław Jerzy Kwasiborski Robert Ryczek Wojciech Lisik Artur Mamcarz |
| author_sort | Małgorzata Buksińska-Lisik |
| collection | DOAJ |
| description | Having the appropriate tools to identify pancreas recipients most susceptible to coronary artery disease (CAD) is crucial for pretransplant cardiological assessment. The aim of this study is to evaluate the association between blood pressure (BP) indices provided by ambulatory blood pressure monitoring (ABPM) and the prevalence of CAD in pancreas transplant candidates with type 1 diabetes (T1D). This prospective cross-sectional study included adult T1D patients referred for pretransplant cardiological assessment in our center. The study population included 86 participants with a median age of 40 (35–46) years. In multivariate logistic regression analyses, after adjusting for potential confounding factors, higher 24 h BP (systolic BP/diastolic BP/pulse pressure) (OR = 1.063, 95% CI 1.023–1.105, <i>p</i> = 0.002/OR = 1.075, 95% CI 1.003–1.153, <i>p</i> = 0.042/OR = 1.091, 95 CI 1.037–1.147, <i>p</i> = 0.001, respectively) and higher daytime BP (systolic BP/diastolic BP/pulse pressure) (OR = 1.069, 95% CI 1.027–1.113, <i>p</i> = 0.001/OR = 1.077, 95% CI 1.002–1.157, <i>p</i> = 0.043/OR = 1.11, 95% CI 1.051–1.172, <i>p</i> = 0.0002, respectively) were independently and significantly associated with the prevalence of CAD. Daytime pulse pressure was the strongest indicator of the prevalence of CAD among all analyzed ABPM parameters. ABPM can be used as a valuable tool to identify pancreas recipients who are most susceptible to CAD. We suggest the inclusion of ABPM in pretransplant cardiac screening in type 1 diabetes patients eligible for pancreas transplantation. |
| first_indexed | 2024-03-10T23:25:54Z |
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| id | doaj.art-93842a4f6e01470daf6fc4364479fb75 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T23:25:54Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-93842a4f6e01470daf6fc4364479fb752023-11-19T07:58:43ZengMDPI AGDiagnostics2075-44182023-08-011317272410.3390/diagnostics13172724Ambulatory Blood Pressure Monitoring as a Useful Tool in the Cardiological Assessment of Pancreas Transplant Recipients with Type 1 DiabetesMałgorzata Buksińska-Lisik0Przemysław Jerzy Kwasiborski1Robert Ryczek2Wojciech Lisik3Artur Mamcarz43rd Department of Internal Medicine and Cardiology, Medical University of Warsaw, 2 Bursztynowa St., 04-749 Warsaw, PolandDepartment of Cardiology and Internal Medicine, Multidisciplinary Hospital Warsaw Miedzylesie, 2 Bursztynowa St., 04-749 Warsaw, PolandDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, 128 Szaserów St., 04-141 Warsaw, PolandDepartment of General and Transplantation Surgery, The Medical University of Warsaw, 59 Nowogrodzka St., 02-006 Warsaw, Poland3rd Department of Internal Medicine and Cardiology, Medical University of Warsaw, 2 Bursztynowa St., 04-749 Warsaw, PolandHaving the appropriate tools to identify pancreas recipients most susceptible to coronary artery disease (CAD) is crucial for pretransplant cardiological assessment. The aim of this study is to evaluate the association between blood pressure (BP) indices provided by ambulatory blood pressure monitoring (ABPM) and the prevalence of CAD in pancreas transplant candidates with type 1 diabetes (T1D). This prospective cross-sectional study included adult T1D patients referred for pretransplant cardiological assessment in our center. The study population included 86 participants with a median age of 40 (35–46) years. In multivariate logistic regression analyses, after adjusting for potential confounding factors, higher 24 h BP (systolic BP/diastolic BP/pulse pressure) (OR = 1.063, 95% CI 1.023–1.105, <i>p</i> = 0.002/OR = 1.075, 95% CI 1.003–1.153, <i>p</i> = 0.042/OR = 1.091, 95 CI 1.037–1.147, <i>p</i> = 0.001, respectively) and higher daytime BP (systolic BP/diastolic BP/pulse pressure) (OR = 1.069, 95% CI 1.027–1.113, <i>p</i> = 0.001/OR = 1.077, 95% CI 1.002–1.157, <i>p</i> = 0.043/OR = 1.11, 95% CI 1.051–1.172, <i>p</i> = 0.0002, respectively) were independently and significantly associated with the prevalence of CAD. Daytime pulse pressure was the strongest indicator of the prevalence of CAD among all analyzed ABPM parameters. ABPM can be used as a valuable tool to identify pancreas recipients who are most susceptible to CAD. We suggest the inclusion of ABPM in pretransplant cardiac screening in type 1 diabetes patients eligible for pancreas transplantation.https://www.mdpi.com/2075-4418/13/17/2724type 1 diabeteshypertensionABPMpancreas transplantationpancreas–kidney transplantationcoronary artery disease |
| spellingShingle | Małgorzata Buksińska-Lisik Przemysław Jerzy Kwasiborski Robert Ryczek Wojciech Lisik Artur Mamcarz Ambulatory Blood Pressure Monitoring as a Useful Tool in the Cardiological Assessment of Pancreas Transplant Recipients with Type 1 Diabetes Diagnostics type 1 diabetes hypertension ABPM pancreas transplantation pancreas–kidney transplantation coronary artery disease |
| title | Ambulatory Blood Pressure Monitoring as a Useful Tool in the Cardiological Assessment of Pancreas Transplant Recipients with Type 1 Diabetes |
| title_full | Ambulatory Blood Pressure Monitoring as a Useful Tool in the Cardiological Assessment of Pancreas Transplant Recipients with Type 1 Diabetes |
| title_fullStr | Ambulatory Blood Pressure Monitoring as a Useful Tool in the Cardiological Assessment of Pancreas Transplant Recipients with Type 1 Diabetes |
| title_full_unstemmed | Ambulatory Blood Pressure Monitoring as a Useful Tool in the Cardiological Assessment of Pancreas Transplant Recipients with Type 1 Diabetes |
| title_short | Ambulatory Blood Pressure Monitoring as a Useful Tool in the Cardiological Assessment of Pancreas Transplant Recipients with Type 1 Diabetes |
| title_sort | ambulatory blood pressure monitoring as a useful tool in the cardiological assessment of pancreas transplant recipients with type 1 diabetes |
| topic | type 1 diabetes hypertension ABPM pancreas transplantation pancreas–kidney transplantation coronary artery disease |
| url | https://www.mdpi.com/2075-4418/13/17/2724 |
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