MELK is a prognostic biomarker and correlated with immune infiltration in glioma

MELK is a prognostic biomarker and correlated with immune infiltration in glioma

ObjectiveGlioma accounts for the vast majority of primary brain tumors with inevitable recurrence and poor prognosis. Maternal embryonic leucine zipper kinase (MELK) is overexpressed in multiple human tumors and could activate a variety of oncogenic-associated signal pathways. However, its role in t...

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Bibliographic Details
Main Authors: Haiyan Yang, Huandi Zhou, Guohui Wang, Lei Tian, Haonan Li, Yufeng Zhang, Xiaoying Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Neurology
Subjects:
glioma
MELK
prognosis
tumor microenvironment
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.977180/full

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