Regulation of interferon-β by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBM.

Regulation of interferon-β by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBM.

The NS1 protein from avian influenza A viruses contains a PDZ binding motif (PBM) at its carboxyl terminus with the consensus sequence ESEV. The ESEV PBM confers binding to several cellular PDZ proteins, including Dlg1, MAGI-1 and Scribble. The interaction between NS1 and Scribble protects infected...

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Bibliographic Details
Main Authors: Manish Kumar, Hongbing Liu, Andrew P Rice
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22911767/pdf/?tool=EBI

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