Effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor)
The study was conducted to evaluate the effect of water temperatures and intraperitoneal administration of microcystins (MCs) on the pharmacokinetics characteristics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) by RP-HPLC method. The results showed that EGCG was...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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EDP Sciences
2021-01-01
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| Series: | E3S Web of Conferences |
| Online Access: | https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/37/e3sconf_icemee2021_02028.pdf |
| _version_ | 1818645214881906688 |
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| author | Dong Xiao-Chen Ye Lu-Ting Zhao Jin Wan Wang-Jun Deng Tong-Le Ge Jian |
| author_facet | Dong Xiao-Chen Ye Lu-Ting Zhao Jin Wan Wang-Jun Deng Tong-Le Ge Jian |
| author_sort | Dong Xiao-Chen |
| collection | DOAJ |
| description | The study was conducted to evaluate the effect of water temperatures and intraperitoneal administration of microcystins (MCs) on the pharmacokinetics characteristics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) by RP-HPLC method. The results showed that EGCG was absorbed and eliminated more faster at 20ºC than at 10ºC. Then the detected results also showed that EGCG was significantly absorbed fast in MCs-treated group than in control group. However, EGCG elimination became very lowly in MCs-treated group. Therefore, the pharmacokinetic characteristics of EGCG were significantly affected by water temperature and MCs toxin. |
| first_indexed | 2024-12-17T00:27:12Z |
| format | Article |
| id | doaj.art-938e1d56815143658d03155f7625ee17 |
| institution | Directory Open Access Journal |
| issn | 2267-1242 |
| language | English |
| last_indexed | 2024-12-17T00:27:12Z |
| publishDate | 2021-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | E3S Web of Conferences |
| spelling | doaj.art-938e1d56815143658d03155f7625ee172022-12-21T22:10:26ZengEDP SciencesE3S Web of Conferences2267-12422021-01-012610202810.1051/e3sconf/202126102028e3sconf_icemee2021_02028Effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor)Dong Xiao-Chen0Ye Lu-Ting1Zhao Jin2Wan Wang-Jun3Deng Tong-Le4Ge Jian5College of Life Sciences, China JiLiang UniversityCollege of Life Sciences, China JiLiang UniversityCollege of Life Sciences, China JiLiang UniversityTechnology center of Hangzhou Customs District P. R. ChinaCollege of Life Sciences, China JiLiang UniversityCollege of Life Sciences, China JiLiang UniversityThe study was conducted to evaluate the effect of water temperatures and intraperitoneal administration of microcystins (MCs) on the pharmacokinetics characteristics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) by RP-HPLC method. The results showed that EGCG was absorbed and eliminated more faster at 20ºC than at 10ºC. Then the detected results also showed that EGCG was significantly absorbed fast in MCs-treated group than in control group. However, EGCG elimination became very lowly in MCs-treated group. Therefore, the pharmacokinetic characteristics of EGCG were significantly affected by water temperature and MCs toxin.https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/37/e3sconf_icemee2021_02028.pdf |
| spellingShingle | Dong Xiao-Chen Ye Lu-Ting Zhao Jin Wan Wang-Jun Deng Tong-Le Ge Jian Effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) E3S Web of Conferences |
| title | Effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) |
| title_full | Effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) |
| title_fullStr | Effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) |
| title_full_unstemmed | Effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) |
| title_short | Effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) |
| title_sort | effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate egcg in snakehead fish ophiocephalus argus cantor |
| url | https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/37/e3sconf_icemee2021_02028.pdf |
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