Hepatitis A and E among immigrants and refugees in Central Brazil
ABSTRACT OBJECTIVE To estimate the prevalence of hepatitis A virus (HAV) and hepatitis E virus (HEV) among immigrants and refugees in Goiás, Central Brazil. METHODS Overall, 355 individuals were interviewed, and blood samples were tested for anti-HAV and anti-HEV IgG. Anti-HEV-positive samples w...
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| Format: | Article |
| Language: | English |
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Universidade de São Paulo
2022-04-01
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| Series: | Revista de Saúde Pública |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102022000100224&tlng=en |
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| author | Grazielle Rosa da Costa e Silva Thaynara Lorrane Silva Martins Carla de Almeida Silva Karlla Antonieta Amorim Caetano Megmar Aparecida dos Santos Carneiro Bruno Vinicius Diniz e Silva Leonora Rezende Pacheco Livia Melo Villar Vanessa Salete de Paula Regina Maria Bringel Martins Sheila Araújo Teles |
| author_facet | Grazielle Rosa da Costa e Silva Thaynara Lorrane Silva Martins Carla de Almeida Silva Karlla Antonieta Amorim Caetano Megmar Aparecida dos Santos Carneiro Bruno Vinicius Diniz e Silva Leonora Rezende Pacheco Livia Melo Villar Vanessa Salete de Paula Regina Maria Bringel Martins Sheila Araújo Teles |
| author_sort | Grazielle Rosa da Costa e Silva |
| collection | DOAJ |
| description | ABSTRACT OBJECTIVE To estimate the prevalence of hepatitis A virus (HAV) and hepatitis E virus (HEV) among immigrants and refugees in Goiás, Central Brazil. METHODS Overall, 355 individuals were interviewed, and blood samples were tested for anti-HAV and anti-HEV IgG. Anti-HEV-positive samples were similarly tested for HEV RNA. RESULTS All participants were from Latin American countries, most of whom, young adult males. The overall anti-HAV IgG prevalence was 87.4% (95%CI: 83.5–90.4), of whom 94.9%, 75.6%, and 60% were from Haiti, Venezuela, and other Latin American countries, respectively (p < 0.001). Age above 19 years and more than 36 months residing in Brazil were associated with a higher prevalence of previous HAV and HEV infection, respectively. Of the children eligible for HAV vaccination according to the National Immunization Program, only eight (44%) had been vaccinated. The overall anti-HEV IgG prevalence was 6.5% (95%CI: 4.4–9.5). All anti-HEV IgG-positive individuals were Haitians, including a child born in Brazil. HEV RNA was detected in two of the anti-HEV IgG-positive samples. CONCLUSION The survey detected a high prevalence of anti-HAV and anti-HEV IgG among immigrants and refugees, and active HEV infection among some Haitian participants. Prevention measures are urgently required to interrupt enteric virus transmission in this emergent and vulnerable population. |
| first_indexed | 2024-12-10T09:55:20Z |
| format | Article |
| id | doaj.art-938fa2540a164ff19e4a495c5e47d7b4 |
| institution | Directory Open Access Journal |
| issn | 1518-8787 |
| language | English |
| last_indexed | 2024-12-10T09:55:20Z |
| publishDate | 2022-04-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Revista de Saúde Pública |
| spelling | doaj.art-938fa2540a164ff19e4a495c5e47d7b42022-12-22T01:53:31ZengUniversidade de São PauloRevista de Saúde Pública1518-87872022-04-015610.11606/s1518-8787.2022056003839Hepatitis A and E among immigrants and refugees in Central BrazilGrazielle Rosa da Costa e Silvahttps://orcid.org/0000-0003-3462-8050Thaynara Lorrane Silva Martinshttps://orcid.org/0000-0001-9949-0473Carla de Almeida Silvahttps://orcid.org/0000-0002-7225-6502Karlla Antonieta Amorim Caetanohttps://orcid.org/0000-0003-4818-4753Megmar Aparecida dos Santos Carneirohttps://orcid.org/0000-0003-0569-477XBruno Vinicius Diniz e Silvahttps://orcid.org/0000-0002-6477-9733Leonora Rezende Pachecohttps://orcid.org/0000-0001-6048-3911Livia Melo Villarhttps://orcid.org/0000-0001-7644-8969Vanessa Salete de Paulahttps://orcid.org/0000-0002-6314-754XRegina Maria Bringel Martinshttps://orcid.org/0000-0001-8941-8531Sheila Araújo Teleshttps://orcid.org/0000-0002-7059-4241ABSTRACT OBJECTIVE To estimate the prevalence of hepatitis A virus (HAV) and hepatitis E virus (HEV) among immigrants and refugees in Goiás, Central Brazil. METHODS Overall, 355 individuals were interviewed, and blood samples were tested for anti-HAV and anti-HEV IgG. Anti-HEV-positive samples were similarly tested for HEV RNA. RESULTS All participants were from Latin American countries, most of whom, young adult males. The overall anti-HAV IgG prevalence was 87.4% (95%CI: 83.5–90.4), of whom 94.9%, 75.6%, and 60% were from Haiti, Venezuela, and other Latin American countries, respectively (p < 0.001). Age above 19 years and more than 36 months residing in Brazil were associated with a higher prevalence of previous HAV and HEV infection, respectively. Of the children eligible for HAV vaccination according to the National Immunization Program, only eight (44%) had been vaccinated. The overall anti-HEV IgG prevalence was 6.5% (95%CI: 4.4–9.5). All anti-HEV IgG-positive individuals were Haitians, including a child born in Brazil. HEV RNA was detected in two of the anti-HEV IgG-positive samples. CONCLUSION The survey detected a high prevalence of anti-HAV and anti-HEV IgG among immigrants and refugees, and active HEV infection among some Haitian participants. Prevention measures are urgently required to interrupt enteric virus transmission in this emergent and vulnerable population.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102022000100224&tlng=enRefugeesLatin AmericaHepatitis A, epidemiologyHepatitis E, epidemiologySeroepidemiologic Studies |
| spellingShingle | Grazielle Rosa da Costa e Silva Thaynara Lorrane Silva Martins Carla de Almeida Silva Karlla Antonieta Amorim Caetano Megmar Aparecida dos Santos Carneiro Bruno Vinicius Diniz e Silva Leonora Rezende Pacheco Livia Melo Villar Vanessa Salete de Paula Regina Maria Bringel Martins Sheila Araújo Teles Hepatitis A and E among immigrants and refugees in Central Brazil Revista de Saúde Pública Refugees Latin America Hepatitis A, epidemiology Hepatitis E, epidemiology Seroepidemiologic Studies |
| title | Hepatitis A and E among immigrants and refugees in Central Brazil |
| title_full | Hepatitis A and E among immigrants and refugees in Central Brazil |
| title_fullStr | Hepatitis A and E among immigrants and refugees in Central Brazil |
| title_full_unstemmed | Hepatitis A and E among immigrants and refugees in Central Brazil |
| title_short | Hepatitis A and E among immigrants and refugees in Central Brazil |
| title_sort | hepatitis a and e among immigrants and refugees in central brazil |
| topic | Refugees Latin America Hepatitis A, epidemiology Hepatitis E, epidemiology Seroepidemiologic Studies |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102022000100224&tlng=en |
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