Staphylococcus aureus and methicillin resistance in Switzerland: regional differences and trends from 2004 to 2014
BACKGROUND: The global epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) is heterogeneous. The objective of this study was to evaluate MRSA epidemiology in Switzerland over an 11-year period. METHODS: We conducted a retrospective study with time series analysis on S. aur...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2016-09-01
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| Series: | Swiss Medical Weekly |
| Subjects: | |
| Online Access: | https://www.smw.ch/index.php/smw/article/view/2220 |
| _version_ | 1811194363101839360 |
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| author | Flaminia Olearo Werner C. Albrich Nathalie Vernaz Stephan Harbarth Andreas Kronenberg Swiss Centre for Antibiotic resistance (ANRESIS) |
| author_facet | Flaminia Olearo Werner C. Albrich Nathalie Vernaz Stephan Harbarth Andreas Kronenberg Swiss Centre for Antibiotic resistance (ANRESIS) |
| author_sort | Flaminia Olearo |
| collection | DOAJ |
| description |
BACKGROUND: The global epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) is heterogeneous. The objective of this study was to evaluate MRSA epidemiology in Switzerland over an 11-year period.
METHODS: We conducted a retrospective study with time series analysis on S. aureus including MRSA and non-multidrug resistant MRSA (NmMRSA). We used NmMRSA as a marker for community-acquired MRSA. NmMRSA was defined as MRSA susceptible to at least three of the following agents: ciprofloxacin, clindamycin, tetracycline and trimethoprim-sulfamethoxazole.
RESULTS: A total of 14 648 MRSA and 115 917 methicillin-susceptible S. aureus (MSSA) isolates were included. Despite an overall decrease of the proportion of MRSA among S. aureus clinical isolates (from 14% in 2004 to 8% in 2014), an increasing trend in NmMRSA was observed. Variations in geographical distribution were noted, with a decrease in the proportion of MRSA in the Italian- and French-speaking regions (from 20–26% in 2004 to 12% in 2014) and low prevalence (3–5%) in the German-speaking region. We noticed an increase in the proportion of MRSA in outpatients (+0.03% per quarter per year) and in the younger population (+0.05% per quarter per year) compared with a decreasing trend in inpatients and the elderly.
CONCLUSION: The proportion of MRSA among S. aureus isolates in Switzerland decreased overall from 2004 to 2014. Worrisome increases of NmMRSA were found in younger persons and outpatients.
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| first_indexed | 2024-04-12T00:24:26Z |
| format | Article |
| id | doaj.art-9394ca32ad27401291433a9024c1560b |
| institution | Directory Open Access Journal |
| issn | 1424-3997 |
| language | English |
| last_indexed | 2024-04-12T00:24:26Z |
| publishDate | 2016-09-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj.art-9394ca32ad27401291433a9024c1560b2022-12-22T03:55:34ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972016-09-01146373810.4414/smw.2016.14339Staphylococcus aureus and methicillin resistance in Switzerland: regional differences and trends from 2004 to 2014Flaminia OlearoWerner C. AlbrichNathalie VernazStephan HarbarthAndreas KronenbergSwiss Centre for Antibiotic resistance (ANRESIS) BACKGROUND: The global epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) is heterogeneous. The objective of this study was to evaluate MRSA epidemiology in Switzerland over an 11-year period. METHODS: We conducted a retrospective study with time series analysis on S. aureus including MRSA and non-multidrug resistant MRSA (NmMRSA). We used NmMRSA as a marker for community-acquired MRSA. NmMRSA was defined as MRSA susceptible to at least three of the following agents: ciprofloxacin, clindamycin, tetracycline and trimethoprim-sulfamethoxazole. RESULTS: A total of 14 648 MRSA and 115 917 methicillin-susceptible S. aureus (MSSA) isolates were included. Despite an overall decrease of the proportion of MRSA among S. aureus clinical isolates (from 14% in 2004 to 8% in 2014), an increasing trend in NmMRSA was observed. Variations in geographical distribution were noted, with a decrease in the proportion of MRSA in the Italian- and French-speaking regions (from 20–26% in 2004 to 12% in 2014) and low prevalence (3–5%) in the German-speaking region. We noticed an increase in the proportion of MRSA in outpatients (+0.03% per quarter per year) and in the younger population (+0.05% per quarter per year) compared with a decreasing trend in inpatients and the elderly. CONCLUSION: The proportion of MRSA among S. aureus isolates in Switzerland decreased overall from 2004 to 2014. Worrisome increases of NmMRSA were found in younger persons and outpatients. https://www.smw.ch/index.php/smw/article/view/2220bacteremiaMRSAMSSANonmultidrug-MRSAtimes series analysistrend |
| spellingShingle | Flaminia Olearo Werner C. Albrich Nathalie Vernaz Stephan Harbarth Andreas Kronenberg Swiss Centre for Antibiotic resistance (ANRESIS) Staphylococcus aureus and methicillin resistance in Switzerland: regional differences and trends from 2004 to 2014 Swiss Medical Weekly bacteremia MRSA MSSA Nonmultidrug-MRSA times series analysis trend |
| title | Staphylococcus aureus and methicillin resistance in Switzerland: regional differences and trends from 2004 to 2014 |
| title_full | Staphylococcus aureus and methicillin resistance in Switzerland: regional differences and trends from 2004 to 2014 |
| title_fullStr | Staphylococcus aureus and methicillin resistance in Switzerland: regional differences and trends from 2004 to 2014 |
| title_full_unstemmed | Staphylococcus aureus and methicillin resistance in Switzerland: regional differences and trends from 2004 to 2014 |
| title_short | Staphylococcus aureus and methicillin resistance in Switzerland: regional differences and trends from 2004 to 2014 |
| title_sort | staphylococcus aureus and methicillin resistance in switzerland regional differences and trends from 2004 to 2014 |
| topic | bacteremia MRSA MSSA Nonmultidrug-MRSA times series analysis trend |
| url | https://www.smw.ch/index.php/smw/article/view/2220 |
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