Are We Giving Optimal Dose of Efavirenz?
Antiretroviral is one of the drugs that extensively been studied for its drug-to- drug interaction. Its long term used and the fact that many HIV-infected patients came in the late stage of disease make polypharmacy is unavoidable. Efavirenz is one of antiretroviral drugs that widely used in HI...
| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Interna Publishing
2016-09-01
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| Series: | Acta Medica Indonesiana |
| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/130 |
| _version_ | 1818364643929751552 |
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| author | Evy Yunihastuti |
| author_facet | Evy Yunihastuti |
| author_sort | Evy Yunihastuti |
| collection | DOAJ |
| description | Antiretroviral is one of the drugs that
extensively been studied for its drug-to- drug
interaction. Its long term used and the fact that
many HIV-infected patients came in the late stage
of disease make polypharmacy is unavoidable.
Efavirenz is one of antiretroviral drugs that
widely used in HIV-infected patients age more
than 3 years old in many countries. Latest
Indonesian antiretroviral guidelines recommend
a combination of tenofovir, lamivudine and
efavirenz given orally in one daily dose as
the preferred primary fixed-drug combination
treatment. This recommendation is based on
many evidence supporting efficacy, tolerability,
price, pregnancy safety, simplicity and the
availability of the drug that will support the
continuing comprehensive care for HIV-infected
patients in primary care level. |
| first_indexed | 2024-12-13T22:07:38Z |
| format | Article |
| id | doaj.art-93965f3842b84ddd9838ebb42c9abe08 |
| institution | Directory Open Access Journal |
| issn | 0125-9326 2338-2732 |
| language | English |
| last_indexed | 2024-12-13T22:07:38Z |
| publishDate | 2016-09-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj.art-93965f3842b84ddd9838ebb42c9abe082022-12-21T23:29:48ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322016-09-01481127Are We Giving Optimal Dose of Efavirenz?Evy Yunihastuti0Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.Antiretroviral is one of the drugs that extensively been studied for its drug-to- drug interaction. Its long term used and the fact that many HIV-infected patients came in the late stage of disease make polypharmacy is unavoidable. Efavirenz is one of antiretroviral drugs that widely used in HIV-infected patients age more than 3 years old in many countries. Latest Indonesian antiretroviral guidelines recommend a combination of tenofovir, lamivudine and efavirenz given orally in one daily dose as the preferred primary fixed-drug combination treatment. This recommendation is based on many evidence supporting efficacy, tolerability, price, pregnancy safety, simplicity and the availability of the drug that will support the continuing comprehensive care for HIV-infected patients in primary care level.http://www.actamedindones.org/index.php/ijim/article/view/130 |
| spellingShingle | Evy Yunihastuti Are We Giving Optimal Dose of Efavirenz? Acta Medica Indonesiana |
| title | Are We Giving Optimal Dose of Efavirenz? |
| title_full | Are We Giving Optimal Dose of Efavirenz? |
| title_fullStr | Are We Giving Optimal Dose of Efavirenz? |
| title_full_unstemmed | Are We Giving Optimal Dose of Efavirenz? |
| title_short | Are We Giving Optimal Dose of Efavirenz? |
| title_sort | are we giving optimal dose of efavirenz |
| url | http://www.actamedindones.org/index.php/ijim/article/view/130 |
| work_keys_str_mv | AT evyyunihastuti arewegivingoptimaldoseofefavirenz |