Cobalt Complex with Thiazole-Based Ligand as New Pseudomonas aeruginosa Quorum Quencher, Biofilm Inhibitor and Virulence Attenuator

Cobalt Complex with Thiazole-Based Ligand as New Pseudomonas aeruginosa Quorum Quencher, Biofilm Inhibitor and Virulence Attenuator

Pseudomonas aeruginosa is one of the most dreaded human pathogens, because of its intrinsic resistance to a number of commonly used antibiotics and ability to form sessile communities (biofilms). Innovative treatment strategies are required and that can rely on the attenuation of the pathogenicity a...

Full description

Bibliographic Details
Main Authors: Anabela Borges, Manuel Simões, Tamara R. Todorović, Nenad R. Filipović, Alfonso T. García-Sosa
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
antibacterial resistance
antivirulence/antipathogenic compounds
biofilm prevention
cobalt complex
furvina
pyocyanin
pyoverdine
quorum sensing inhibition
transcriptional activator protein LasR
Online Access:http://www.mdpi.com/1420-3049/23/6/1385

Internet

http://www.mdpi.com/1420-3049/23/6/1385

Similar Items