Vaccine-Mediated Mechanisms Controlling <i>Francisella tularensis</i> SCHU S4 Growth in a Rat Co-Culture System

Vaccine-Mediated Mechanisms Controlling <i>Francisella tularensis</i> SCHU S4 Growth in a Rat Co-Culture System

<i>Francisella tularensis</i> causes the severe disease tularemia. In the present study, the aim was to identify correlates of protection in the rat co-culture model by investigating the immune responses using two vaccine candidates conferring distinct degrees of protection in rat and mo...

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Bibliographic Details
Main Authors: Helena Lindgren, Kjell Eneslätt, Igor Golovliov, Carl Gelhaus, Patrik Rydén, Terry Wu, Anders Sjöstedt
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pathogens
Subjects:
<i>Francisella tularensis</i>
SCHU S4
in vitro co-culture model
rat immune response
correlates of protection
nitrite
Online Access:https://www.mdpi.com/2076-0817/9/5/338

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