Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions
ObjectivesThe Kaiser scoring system for breast magnetic resonance imaging is a clinical decision-making tool for diagnosing breast lesions. However, the Kaiser score (KS) did not include the evaluation of breast vascularity. Therefore, this study aimed to use KS combined with breast vascular assessm...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1165405/full |
| _version_ | 1797785594094419968 |
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| author | Xin-zhu Zhou Lian-hua Liu Shuang He Hui-fang Yao Li-ping Chen Chen Deng Shuang-Ling Li Xiao-yong Zhang Hua Lai |
| author_facet | Xin-zhu Zhou Lian-hua Liu Shuang He Hui-fang Yao Li-ping Chen Chen Deng Shuang-Ling Li Xiao-yong Zhang Hua Lai |
| author_sort | Xin-zhu Zhou |
| collection | DOAJ |
| description | ObjectivesThe Kaiser scoring system for breast magnetic resonance imaging is a clinical decision-making tool for diagnosing breast lesions. However, the Kaiser score (KS) did not include the evaluation of breast vascularity. Therefore, this study aimed to use KS combined with breast vascular assessment, defined as KS*, and investigate the effectiveness of KS* in differentiating benign from malignant breast lesions.MethodsThis retrospective study included 223 patients with suspicious breast lesions and pathologically verified results. The histopathological diagnostic criteria were according to the fifth edition of the WHO classification of breast tumors. The KS* was obtained after a joint evaluation combining the original KS and breast vasculature assessment. The receiver operating characteristic (ROC) curve was used for comparing differences in the diagnostic performance between KS* and KS, and the area under the receiver operating characteristic (AUC) was compared.ResultsThere were 119 (53.4%) benign and 104 (46.6%) malignant lesions in total. The overall sensitivity, specificity, and accuracy of increased ipsilateral breast vascularity were 69.2%, 76.5%, and 73.1%, respectively. The overall sensitivity, specificity, and accuracy of AVS were 82.7%, 76.5%, and 79.4%, respectively. For all lesions included the AUC of KS* was greater than that of KS (0.877 vs. 0.858, P = 0.016). The largest difference in AUC was observed in the non-mass subgroup (0.793 vs. 0.725, P = 0.029).ConclusionIpsilaterally increased breast vascularity and a positive AVS sign were significantly associated with malignancy. KS combined with breast vascular assessment can effectively improve the diagnostic ability of KS for breast lesions, especially for non-mass lesions. |
| first_indexed | 2024-03-13T00:56:15Z |
| format | Article |
| id | doaj.art-939bb246466d4bdeb474dee5b74cb959 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-13T00:56:15Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-939bb246466d4bdeb474dee5b74cb9592023-07-06T20:13:38ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-07-011310.3389/fonc.2023.11654051165405Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesionsXin-zhu Zhou0Lian-hua Liu1Shuang He2Hui-fang Yao3Li-ping Chen4Chen Deng5Shuang-Ling Li6Xiao-yong Zhang7Hua Lai8Department of Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaClinical Science, Philips Healthcare, Chengdu, ChinaDepartment of Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaObjectivesThe Kaiser scoring system for breast magnetic resonance imaging is a clinical decision-making tool for diagnosing breast lesions. However, the Kaiser score (KS) did not include the evaluation of breast vascularity. Therefore, this study aimed to use KS combined with breast vascular assessment, defined as KS*, and investigate the effectiveness of KS* in differentiating benign from malignant breast lesions.MethodsThis retrospective study included 223 patients with suspicious breast lesions and pathologically verified results. The histopathological diagnostic criteria were according to the fifth edition of the WHO classification of breast tumors. The KS* was obtained after a joint evaluation combining the original KS and breast vasculature assessment. The receiver operating characteristic (ROC) curve was used for comparing differences in the diagnostic performance between KS* and KS, and the area under the receiver operating characteristic (AUC) was compared.ResultsThere were 119 (53.4%) benign and 104 (46.6%) malignant lesions in total. The overall sensitivity, specificity, and accuracy of increased ipsilateral breast vascularity were 69.2%, 76.5%, and 73.1%, respectively. The overall sensitivity, specificity, and accuracy of AVS were 82.7%, 76.5%, and 79.4%, respectively. For all lesions included the AUC of KS* was greater than that of KS (0.877 vs. 0.858, P = 0.016). The largest difference in AUC was observed in the non-mass subgroup (0.793 vs. 0.725, P = 0.029).ConclusionIpsilaterally increased breast vascularity and a positive AVS sign were significantly associated with malignancy. KS combined with breast vascular assessment can effectively improve the diagnostic ability of KS for breast lesions, especially for non-mass lesions.https://www.frontiersin.org/articles/10.3389/fonc.2023.1165405/fullbreastbreast neoplasmsmagnetic resonance imagingclinical decision makingbreast cancer |
| spellingShingle | Xin-zhu Zhou Lian-hua Liu Shuang He Hui-fang Yao Li-ping Chen Chen Deng Shuang-Ling Li Xiao-yong Zhang Hua Lai Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions Frontiers in Oncology breast breast neoplasms magnetic resonance imaging clinical decision making breast cancer |
| title | Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
| title_full | Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
| title_fullStr | Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
| title_full_unstemmed | Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
| title_short | Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
| title_sort | diagnostic value of kaiser score combined with breast vascular assessment from breast mri for the characterization of breast lesions |
| topic | breast breast neoplasms magnetic resonance imaging clinical decision making breast cancer |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1165405/full |
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