RNA Based COVID-19 Vaccine Candidates in Clinical Phase

The number of cases and disease-dependent deaths continue to increase worldwide due to the COVID-19 infection accepted as a global pandemic by the World Health Organization on March 11, 2020. Therefore, the antivirals used in treatment and vaccines that are the most effective weapons for protection...

Full description

Bibliographic Details
Main Authors: Leyla İpek Rudvan Al, Meliha Çağla Sönmezer, Serhat Ünal
Format: Article
Language:English
Published: Bilimsel Tip Yayinevi 2021-06-01
Series:Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Subjects:
Online Access:http://floradergisi.org/managete/fu_folder/2021-02/227-231%20Leyla%20ipek%20Rudvan%20Al.pdf
_version_ 1797915678689198080
author Leyla İpek Rudvan Al
Meliha Çağla Sönmezer
Serhat Ünal
author_facet Leyla İpek Rudvan Al
Meliha Çağla Sönmezer
Serhat Ünal
author_sort Leyla İpek Rudvan Al
collection DOAJ
description The number of cases and disease-dependent deaths continue to increase worldwide due to the COVID-19 infection accepted as a global pandemic by the World Health Organization on March 11, 2020. Therefore, the antivirals used in treatment and vaccines that are the most effective weapons for protection remain the most popular topic on the agenda. There are a few conditions that might have an impact on the course of the pandemic, including the mutation of the virus and losing its ability to cause disease, generating herd immunity by reaching a critical rate of immunized people in the community due to the disease, and ensuring herd immunity through effective vaccination. Vaccine trials, which have started owing to the severity and urgency of the situation we are in, continue highly rapidly and effectively. According to the March 2, 2021 data of WHO, there are 258 vaccine trials, 76 of which are at the clinical phase, and 9 of the vaccine trials that are at the clinical phase are RNA-based vaccines. In our study, it was aimed to investigate RNA-based COVID-19 vaccine candidates and review their current data.
first_indexed 2024-04-10T12:46:24Z
format Article
id doaj.art-939cb4bd83d34f11a227fda2ac744fae
institution Directory Open Access Journal
issn 1300-932X
1300-932X
language English
last_indexed 2024-04-10T12:46:24Z
publishDate 2021-06-01
publisher Bilimsel Tip Yayinevi
record_format Article
series Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
spelling doaj.art-939cb4bd83d34f11a227fda2ac744fae2023-02-15T16:14:04ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2021-06-0126222723110.5578/flora.20219802RNA Based COVID-19 Vaccine Candidates in Clinical PhaseLeyla İpek Rudvan Al0https://orcid.org/0000-0002-7261-6512Meliha Çağla Sönmezer1https://orcid.org/0000-0001-6657-1779Serhat Ünal2https://orcid.org/0000-0003-1184-4711Department of Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, TurkeyDepartment of Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, TurkeyDepartment of Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, TurkeyThe number of cases and disease-dependent deaths continue to increase worldwide due to the COVID-19 infection accepted as a global pandemic by the World Health Organization on March 11, 2020. Therefore, the antivirals used in treatment and vaccines that are the most effective weapons for protection remain the most popular topic on the agenda. There are a few conditions that might have an impact on the course of the pandemic, including the mutation of the virus and losing its ability to cause disease, generating herd immunity by reaching a critical rate of immunized people in the community due to the disease, and ensuring herd immunity through effective vaccination. Vaccine trials, which have started owing to the severity and urgency of the situation we are in, continue highly rapidly and effectively. According to the March 2, 2021 data of WHO, there are 258 vaccine trials, 76 of which are at the clinical phase, and 9 of the vaccine trials that are at the clinical phase are RNA-based vaccines. In our study, it was aimed to investigate RNA-based COVID-19 vaccine candidates and review their current data.http://floradergisi.org/managete/fu_folder/2021-02/227-231%20Leyla%20ipek%20Rudvan%20Al.pdfrna based vaccinescovid-19
spellingShingle Leyla İpek Rudvan Al
Meliha Çağla Sönmezer
Serhat Ünal
RNA Based COVID-19 Vaccine Candidates in Clinical Phase
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
rna based vaccines
covid-19
title RNA Based COVID-19 Vaccine Candidates in Clinical Phase
title_full RNA Based COVID-19 Vaccine Candidates in Clinical Phase
title_fullStr RNA Based COVID-19 Vaccine Candidates in Clinical Phase
title_full_unstemmed RNA Based COVID-19 Vaccine Candidates in Clinical Phase
title_short RNA Based COVID-19 Vaccine Candidates in Clinical Phase
title_sort rna based covid 19 vaccine candidates in clinical phase
topic rna based vaccines
covid-19
url http://floradergisi.org/managete/fu_folder/2021-02/227-231%20Leyla%20ipek%20Rudvan%20Al.pdf
work_keys_str_mv AT leylaipekrudvanal rnabasedcovid19vaccinecandidatesinclinicalphase
AT melihacaglasonmezer rnabasedcovid19vaccinecandidatesinclinicalphase
AT serhatunal rnabasedcovid19vaccinecandidatesinclinicalphase