RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors
Mature piRNAs are produced from long single-stranded precursor RNAs. Here the authors show that RNase κ generates 2′,3′-cyclic phosphate-containing piRNA precursors and promotes piRNA production.
Bibliographic Details
| Main Authors: |
Megumi Shigematsu,
Takuya Kawamura,
Keisuke Morichika,
Natsuko Izumi,
Takashi Kiuchi,
Shozo Honda,
Venetia Pliatsika,
Ryuma Matsubara,
Isidore Rigoutsos,
Susumu Katsuma,
Yukihide Tomari,
Yohei Kirino |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Portfolio
2021-07-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-021-24681-w
|
|---|