The Mechanism of the Neuroprotective Effect of Kynurenic Acid in the Experimental Model of Neonatal Hypoxia–Ischemia: The Link to Oxidative Stress

The Mechanism of the Neuroprotective Effect of Kynurenic Acid in the Experimental Model of Neonatal Hypoxia–Ischemia: The Link to Oxidative Stress

The over-activation of NMDA receptors and oxidative stress are important components of neonatal hypoxia–ischemia (HI). Kynurenic acid (KYNA) acts as an NMDA receptor antagonist and is known as a reactive oxygen species (ROS) scavenger, which makes it a potential therapeutic compound. This study aime...

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Bibliographic Details
Main Authors:	Ewelina Bratek-Gerej, Apolonia Ziembowicz, Jakub Godlewski, Elzbieta Salinska
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Series:	Antioxidants
Subjects:	neonatal hypoxia–ischemia kynurenic acid (KYNA) oxidative stress neuroprotection
Online Access:	https://www.mdpi.com/2076-3921/10/11/1775

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