Varenicline for smoking cessation: efficacy, safety, and treatment recommendations
Jon O Ebbert, Kirk D Wyatt, J Taylor Hays, Eric W Klee, Richard D HurtMayo Clinic College of Medicine, Rochester, MN, USAAbstract: Smoking is the leading preventable cause of morbidity and mortality in the US, and decreasing smoking prevalence is a public health priority. Patients achieve the greate...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2010-09-01
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| Series: | Patient Preference and Adherence |
| Online Access: | http://www.dovepress.com/varenicline-for-smoking-cessation-efficacy-safety-and-treatment-recomm-a5269 |
| _version_ | 1818210961094344704 |
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| author | Jon O Ebbert Kirk D Wyatt J Taylor Hays et al |
| author_facet | Jon O Ebbert Kirk D Wyatt J Taylor Hays et al |
| author_sort | Jon O Ebbert |
| collection | DOAJ |
| description | Jon O Ebbert, Kirk D Wyatt, J Taylor Hays, Eric W Klee, Richard D HurtMayo Clinic College of Medicine, Rochester, MN, USAAbstract: Smoking is the leading preventable cause of morbidity and mortality in the US, and decreasing smoking prevalence is a public health priority. Patients achieve the greatest success when quit attempts involve behavioral therapy combined with pharmacotherapy. Varenicline is the most recent addition to the pharmacotherapeutic armamentarium for the treatment of tobacco dependence. Varenicline is efficacious and cost-effective. Smoking relapse and adverse treatment-related side effects may decrease medication adherence and patient satisfaction with varenicline. In the clinical setting, varenicline treatment can be optimized by reducing doses in patients who experience intolerable side effects, increasing the dose in partial responders, and providing long-term maintenance therapy for relapse prevention.Keywords: varenicline, tobacco dependence, smoking cessation, nicotine addiction |
| first_indexed | 2024-12-12T05:24:55Z |
| format | Article |
| id | doaj.art-93a5eca4d9964b08bcbdfc80568bb295 |
| institution | Directory Open Access Journal |
| issn | 1177-889X |
| language | English |
| last_indexed | 2024-12-12T05:24:55Z |
| publishDate | 2010-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Patient Preference and Adherence |
| spelling | doaj.art-93a5eca4d9964b08bcbdfc80568bb2952022-12-22T00:36:29ZengDove Medical PressPatient Preference and Adherence1177-889X2010-09-012010default355362Varenicline for smoking cessation: efficacy, safety, and treatment recommendationsJon O EbbertKirk D WyattJ Taylor Hayset alJon O Ebbert, Kirk D Wyatt, J Taylor Hays, Eric W Klee, Richard D HurtMayo Clinic College of Medicine, Rochester, MN, USAAbstract: Smoking is the leading preventable cause of morbidity and mortality in the US, and decreasing smoking prevalence is a public health priority. Patients achieve the greatest success when quit attempts involve behavioral therapy combined with pharmacotherapy. Varenicline is the most recent addition to the pharmacotherapeutic armamentarium for the treatment of tobacco dependence. Varenicline is efficacious and cost-effective. Smoking relapse and adverse treatment-related side effects may decrease medication adherence and patient satisfaction with varenicline. In the clinical setting, varenicline treatment can be optimized by reducing doses in patients who experience intolerable side effects, increasing the dose in partial responders, and providing long-term maintenance therapy for relapse prevention.Keywords: varenicline, tobacco dependence, smoking cessation, nicotine addictionhttp://www.dovepress.com/varenicline-for-smoking-cessation-efficacy-safety-and-treatment-recomm-a5269 |
| spellingShingle | Jon O Ebbert Kirk D Wyatt J Taylor Hays et al Varenicline for smoking cessation: efficacy, safety, and treatment recommendations Patient Preference and Adherence |
| title | Varenicline for smoking cessation: efficacy, safety, and treatment recommendations |
| title_full | Varenicline for smoking cessation: efficacy, safety, and treatment recommendations |
| title_fullStr | Varenicline for smoking cessation: efficacy, safety, and treatment recommendations |
| title_full_unstemmed | Varenicline for smoking cessation: efficacy, safety, and treatment recommendations |
| title_short | Varenicline for smoking cessation: efficacy, safety, and treatment recommendations |
| title_sort | varenicline for smoking cessation efficacy safety and treatment recommendations |
| url | http://www.dovepress.com/varenicline-for-smoking-cessation-efficacy-safety-and-treatment-recomm-a5269 |
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