NAD+ Biosynthesis Impairment and Acute Kidney Injury after Major Vascular Surgery

NAD+ Biosynthesis Impairment and Acute Kidney Injury after Major Vascular Surgery

Acute kidney injury (AKI) is a serious complication after vascular surgery. Reduced synthesis of nicotinamide adenine dinucleotide (NAD+) from tryptophan is associated with an increased risk of AKI in critically ill patients, patients hospitalized with COVID-19, and cardiac surgery patients, and is...

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Bibliographic Details
Main Authors: Annmarie I. Mede, Ginger L. Milne, Dawei Wei, Derek K. Smith, Loren E. Smith
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Antioxidants
Subjects:
AKI
kidney injury
NAD
vascular surgery
quinolinate
Online Access:https://www.mdpi.com/2076-3921/12/4/821

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