Sad1 Spatiotemporally Regulates Kinetochore Clustering To Ensure High-Fidelity Chromosome Segregation in the Human Fungal Pathogen <italic toggle="yes">Cryptococcus neoformans</italic>

Sad1 Spatiotemporally Regulates Kinetochore Clustering To Ensure High-Fidelity Chromosome Segregation in the Human Fungal Pathogen <italic toggle="yes">Cryptococcus neoformans</italic>

ABSTRACT Kinetochore clustering, frequently observed in yeasts, plays a key role in genome organization and chromosome segregation. In the absence of the metaphase plate arrangement, kinetochore clustering in yeast species is believed to facilitate timely kinetochore-microtubule interactions to achi...

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Bibliographic Details
Main Authors: Vikas Yadav, Kaustuv Sanyal
Format: Article
Language:English
Published: American Society for Microbiology 2018-08-01
Series:mSphere
Subjects:
CENP-A
LINC complex
microtubule organizing center
mitotic spindle
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00190-18

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