Motor cortical patterns of upper motor neuron pathology in amyotrophic lateral sclerosis: A 3 T MRI study with iron-sensitive sequences

Motor cortical patterns of upper motor neuron pathology in amyotrophic lateral sclerosis: A 3 T MRI study with iron-sensitive sequences

Background: Patterns of initiation and propagation of disease in Amyotrophic Lateral Sclerosis (ALS) are still partly unknown. Single or multiple foci of neurodegeneration followed by disease diffusion to contiguous or connected regions have been proposed as mechanisms underlying symptom occurrence....

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Bibliographic Details
Main Authors: Graziella Donatelli, Mauro Costagli, Paolo Cecchi, Gianmichele Migaleddu, Francesca Bianchi, Paolo Frumento, Gabriele Siciliano, Mirco Cosottini
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:NeuroImage: Clinical
Subjects:
Amyotrophic lateral sclerosis
Quantitative susceptibility mapping
Magnetic resonance imaging
Primary motor cortex
Upper motor neuron
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158222002030

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http://www.sciencedirect.com/science/article/pii/S2213158222002030

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