Inflammatory and linear verrucous epidermal nevus in vulvar region

Introduction: Inflammatory linear verrucous epidermal nevus (ILVEN) is a variant of verrucous epidermal nevus. It has a psoriasiform or eczematous and itchy aspect, and has differential diagnosis compared to other more common dermatoses; thus, histological studies are often necessary. It mainly aff...

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Main Authors: José Humberto Belmino Chaves, Julia Espíndola Guimarães, José Eleutério Junior
Format: Article
Language:English
Published: Zeppelini Editorial e Comunicacao 2019-05-01
Series:DST
Subjects:
Online Access:https://bjstd.org/revista/article/view/846
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author José Humberto Belmino Chaves
Julia Espíndola Guimarães
José Eleutério Junior
author_facet José Humberto Belmino Chaves
Julia Espíndola Guimarães
José Eleutério Junior
author_sort José Humberto Belmino Chaves
collection DOAJ
description Introduction: Inflammatory linear verrucous epidermal nevus (ILVEN) is a variant of verrucous epidermal nevus. It has a psoriasiform or eczematous and itchy aspect, and has differential diagnosis compared to other more common dermatoses; thus, histological studies are often necessary. It mainly affects women of early age and must be differentiated from condyloma acuminatum. Interestingly, the lower left limb is often involved, but the genital region is rarely affected. Treatment is refractory and the best method is not yet established. Objective: We present a case of unusual vulvar involvement known as inflammatory linear verrucous epidermal nevus. Methods: This was a clinical case report of a child diagnosed with ILVEN in the vulvar region. Case report: An 11-year-old female presented to the gynecology department of the Universidade Federal de Alagoas complaining of pruritic lesions on the large left vulvar lip, perianal and anal regions, and vaginal introitus. The lesions were hypochromic, eroded, and covered by scabs along the Blaschko line with verrucous lesions in the abdomen and upper and lower limbs. These characteristics fit the clinical criteria of Altman and Mehregan, and the histological criteria of Dupre and Christol for diagnosis of ILVEN. The treatment was performed with Vitanol A® and Epidrat Ultra® with partial improvement of the lesions. We chose to excise the lesions to control the condition. Conclusion: These lesions are characterized by recurrent inflammatory phenomena including psoriasiform or eczematous aspects in the extremities with genital involvement being rare. Other common dermatoses are often confused with ILVEN and make anatomically pathological analysis extremely important for diagnosis. Despite details on several types of treatment for ILVEN, there are no studies on relative advantages because this lesion is very refractory to the treatment.
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spelling doaj.art-93ad502c86bb4ab596720c70f9852cd12023-01-28T01:05:56ZengZeppelini Editorial e ComunicacaoDST2177-82642019-05-01311Inflammatory and linear verrucous epidermal nevus in vulvar regionJosé Humberto Belmino ChavesJulia Espíndola GuimarãesJosé Eleutério Junior0Universidade Federal do Ceará Introduction: Inflammatory linear verrucous epidermal nevus (ILVEN) is a variant of verrucous epidermal nevus. It has a psoriasiform or eczematous and itchy aspect, and has differential diagnosis compared to other more common dermatoses; thus, histological studies are often necessary. It mainly affects women of early age and must be differentiated from condyloma acuminatum. Interestingly, the lower left limb is often involved, but the genital region is rarely affected. Treatment is refractory and the best method is not yet established. Objective: We present a case of unusual vulvar involvement known as inflammatory linear verrucous epidermal nevus. Methods: This was a clinical case report of a child diagnosed with ILVEN in the vulvar region. Case report: An 11-year-old female presented to the gynecology department of the Universidade Federal de Alagoas complaining of pruritic lesions on the large left vulvar lip, perianal and anal regions, and vaginal introitus. The lesions were hypochromic, eroded, and covered by scabs along the Blaschko line with verrucous lesions in the abdomen and upper and lower limbs. These characteristics fit the clinical criteria of Altman and Mehregan, and the histological criteria of Dupre and Christol for diagnosis of ILVEN. The treatment was performed with Vitanol A® and Epidrat Ultra® with partial improvement of the lesions. We chose to excise the lesions to control the condition. Conclusion: These lesions are characterized by recurrent inflammatory phenomena including psoriasiform or eczematous aspects in the extremities with genital involvement being rare. Other common dermatoses are often confused with ILVEN and make anatomically pathological analysis extremely important for diagnosis. Despite details on several types of treatment for ILVEN, there are no studies on relative advantages because this lesion is very refractory to the treatment. https://bjstd.org/revista/article/view/846nevuspigmentedneoplasmsvulva
spellingShingle José Humberto Belmino Chaves
Julia Espíndola Guimarães
José Eleutério Junior
Inflammatory and linear verrucous epidermal nevus in vulvar region
DST
nevus
pigmented
neoplasms
vulva
title Inflammatory and linear verrucous epidermal nevus in vulvar region
title_full Inflammatory and linear verrucous epidermal nevus in vulvar region
title_fullStr Inflammatory and linear verrucous epidermal nevus in vulvar region
title_full_unstemmed Inflammatory and linear verrucous epidermal nevus in vulvar region
title_short Inflammatory and linear verrucous epidermal nevus in vulvar region
title_sort inflammatory and linear verrucous epidermal nevus in vulvar region
topic nevus
pigmented
neoplasms
vulva
url https://bjstd.org/revista/article/view/846
work_keys_str_mv AT josehumbertobelminochaves inflammatoryandlinearverrucousepidermalnevusinvulvarregion
AT juliaespindolaguimaraes inflammatoryandlinearverrucousepidermalnevusinvulvarregion
AT joseeleuteriojunior inflammatoryandlinearverrucousepidermalnevusinvulvarregion