Molecular and Cellular Mechanisms of Electronegative Lipoproteins in Cardiovascular Diseases

Molecular and Cellular Mechanisms of Electronegative Lipoproteins in Cardiovascular Diseases

Dysregulation of glucose and lipid metabolism increases plasma levels of lipoproteins and triglycerides, resulting in vascular endothelial damage. Remarkably, the oxidation of lipid and lipoprotein particles generates electronegative lipoproteins that mediate cellular deterioration of atherosclerosi...

Full description

Bibliographic Details
Main Authors:	Liang-Yin Ke, Shi Hui Law, Vineet Kumar Mishra, Farzana Parveen, Hua-Chen Chan, Ye-Hsu Lu, Chih-Sheng Chu
Format:	Article
Language:	English
Published:	MDPI AG 2020-11-01
Series:	Biomedicines
Subjects:	electronegative LDL LDL(−) L5 LDL oxidized LDL oxLDL lectin-like oxLDL receptor-1
Online Access:	https://www.mdpi.com/2227-9059/8/12/550

Similar Items

Clinical Significance of Electronegative Low-Density Lipoprotein Cholesterol in Atherothrombosis
by: Chih-Sheng Chu, et al.
Published: (2020-07-01)

Electronegative LDL Is Associated with Plaque Vulnerability in Patients with Ischemic Stroke and Carotid Atherosclerosis
by: Núria Puig, et al.
Published: (2023-02-01)

The Influence of a Conjugated Pneumococcal Vaccination on Plasma Antibody Levels against Oxidized Low-Density Lipoprotein in Metabolic Disease Patients: A Single-Arm Pilot Clinical Trial
by: Ronit Shiri-Sverdlov, et al.
Published: (2021-01-01)

Comparison of lipid profile parameters and oxidized low-density lipoprotein between normal and preeclamptic pregnancies in a tertiary care hospital in Nepal
by: Timalsina S, et al.
Published: (2016-10-01)

The Placebo-Controlled Effect of Percutaneous Coronary Intervention on Exercise Induced Changes in Anti-Malondialdehyde-LDL Antibody Levels in Stable Coronary Artery Disease: A Substudy of the ORBITA Trial
by: Adam Hartley, et al.
Published: (2021-10-01)

The Initial Human Atherosclerotic Lesion and Lipoprotein Modification—A Deep Connection
by: Michael Torzewski
Published: (2021-10-01)

Efficacy of Hydroxytyrosol-Rich Food Supplements on Reducing Lipid Oxidation in Humans
by: Cecilia Bender, et al.
Published: (2023-03-01)

Homeopathic preparation of Allium sativum abrogates OxLDL mediated atherogenic events in macrophages: An in vitro and in silico approach
by: Thangarajeswari Mohan, et al.
Published: (2024-01-01)

Autoantibodies against modified low density Lipoprotein in patients with coronary heart disease and normal individuals
by: "Mohammadi R, et al.
Published: (2001-12-01)

Autoantibodies against modified low density Lipoprotein in patients with coronary heart disease and normal individuals
by: "Mohammadi R, et al.
Published: (2001-08-01)

TGF-β Isoforms and GDF-15 in the Development and Progression of Atherosclerosis
by: Agnė Liuizė (Abramavičiūtė), et al.
Published: (2024-02-01)

LXRα Regulates oxLDL-Induced Trained Immunity in Macrophages
by: Hannes M. Findeisen, et al.
Published: (2022-05-01)

PACAP regulates VPAC1 expression, inflammatory processes and lipid homeostasis in M1- and M2-macrophages
by: Roman Witzel, et al.
Published: (2023-10-01)

Exposure to oxLDL impairs TGF-β activity in human tendon cells
by: Rouhollah Mousavizadeh, et al.
Published: (2023-03-01)

Phenotype and Response to PAMPs of Human Monocyte-Derived Foam Cells Obtained by Long-Term Culture in the Presence of oxLDLs
by: Anna Nogieć, et al.
Published: (2020-08-01)

PARP inhibition in atherosclerosis and its effects on dendritic cells, T cells and auto-antibody levels
by: Erbel C, et al.
Published: (2011-08-01)

Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages
by: Oscar J. Lara-Guzmán, et al.
Published: (2018-05-01)

Association of anti-oxidized LDL and candidate genes with severity of coronary stenosis in the Women's Ischemia Syndrome Evaluation study
by: Qi Chen, et al.
Published: (2011-04-01)

Effect of Oxidized Low-Density Lipoprotein on Head and Neck Squamous Cell Carcinomas
by: Nadège Kindt, et al.
Published: (2021-05-01)

Oxidized low-density-lipoprotein accumulation is associated with liver fibrosis in experimental cholestasis
by: Güldeniz Karadeniz, et al.
Published: (2008-01-01)

Antioxidant Efficacy of a <i>Spirulina</i> Liquid Extract on Oxidative Stress Status and Metabolic Disturbances in Subjects with Metabolic Syndrome
by: N’Deye Lallah Nina Koite, et al.
Published: (2022-07-01)

Oxidized LDL Modifies the Association between Proteinuria and Deterioration of Kidney Function in Proteinuric Diabetic Kidney Disease
by: Stefanos Roumeliotis, et al.
Published: (2021-05-01)

GRP78/BiP alleviates oxLDL-induced hepatotoxicity in familial hypercholesterolemia caused by missense variants of LDLR in a HepG2 cellular model
by: Divya Saro Varghese, et al.
Published: (2023-05-01)

Serum ox-LDL Level is Reduced with the Extent of Stenosis in Coronary Arteries
by: Mohammad Najafi, et al.
Published: (2013-05-01)

LOX-1-Mediated Effects on Vascular Cells in Atherosclerosis
by: Dimitry A. Chistiakov, et al.
Published: (2016-05-01)

Mipu1 Inhibits Lipid Accumulation Through Down-Regulation of CD36 in RAW264.7 Cells
by: Shun-Lin Qu, et al.
Published: (2015-09-01)

P62 Links the Autophagy Pathway and the Ubiquitin–Proteasome System in Endothelial Cells during Atherosclerosis
by: SeJeong Kim, et al.
Published: (2021-07-01)

Hydroxytyrosol Reduces Foam Cell Formation and Endothelial Inflammation Regulating the PPARγ/LXRα/ABCA1 Pathway
by: Sara Franceschelli, et al.
Published: (2023-01-01)

The impact of reactive oxygen species in the development of cardiometabolic disorders: a review
by: Roland Akhigbe, et al.
Published: (2021-02-01)

Poly (ADP-Ribose) Polymerase 1 Mediated Arginase II Activation Is Responsible for Oxidized LDL-Induced Endothelial Dysfunction
by: Qi Wang, et al.
Published: (2018-08-01)

Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis
by: Anastasia V. Poznyak, et al.
Published: (2021-01-01)

Impact of Glucagon-Like Peptide 1 Receptor Agonists on Biochemical Markers of the Initiation of Atherosclerotic Process
by: Marcin Hachuła, et al.
Published: (2024-02-01)

The Interplay between Atherosclerosis and Cancer: Breast Cancer Cells Increase the Expression of Endothelial Cell Adhesion Markers
by: Alessandro Scalia, et al.
Published: (2023-06-01)

The Effect of a 13-Valent Conjugate Pneumococcal Vaccine on Circulating Antibodies Against Oxidized LDL and Phosphorylcholine in Man, A Randomized Placebo-Controlled Clinical Trial
by: Hendrika W. Grievink, et al.
Published: (2020-10-01)

Development of a Method for Producing oxLDL: Characterization of Their Effects on HPV-Positive Head and Neck Cancer Cells
by: Alessandro Scalia, et al.
Published: (2022-10-01)

Contribution of adipocyte Na/K-ATPase α1/CD36 signaling induced exosome secretion in response to oxidized LDL
by: Sneha S. Pillai, et al.
Published: (2023-04-01)

Role of CD36 in cancer progression, stemness, and targeting
by: Sandra L. Guerrero-Rodríguez, et al.
Published: (2022-12-01)

Detection of circulating IgG antibodies to apolipoprotein B100 in acute myocardial infarction
by: Xueying Zhang, et al.
Published: (2015-01-01)

Elaborate evaluation of serum and tissue oxidized LDL level with darapladib therapy: A feasible diagnostic marker for early atherogenesis
by: Teuku Heriansyah, et al.
Published: (2017-02-01)

Effect of plant sterols compared with ezetimibe on oxidative stress in patients treated with statins
by: Adriana Bertolami, et al.
Published: (2014-09-01)