Retroperitoneal extragonadal germ cell tumor with duodenal infiltration: A challenging endo‐luminal tissue diagnosis

Abstract A 32‐year‐old Malay male was referred to our hospital for a second opinion. An abdominal and pelvic CT scan at the previous medical facility showed a large retroperitoneal tumor, which was subjected to ultrasound‐guided fine‐needle aspiration cytology (FNAC) with a provisional diagnosis of...

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Main Authors: Choon‐Seng Qua, Kaik‐Boo Peh, Saravannan Kannan, Khean‐Lee Goh
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:JGH Open
Subjects:
Online Access:https://doi.org/10.1002/jgh3.12711
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author Choon‐Seng Qua
Kaik‐Boo Peh
Saravannan Kannan
Khean‐Lee Goh
author_facet Choon‐Seng Qua
Kaik‐Boo Peh
Saravannan Kannan
Khean‐Lee Goh
author_sort Choon‐Seng Qua
collection DOAJ
description Abstract A 32‐year‐old Malay male was referred to our hospital for a second opinion. An abdominal and pelvic CT scan at the previous medical facility showed a large retroperitoneal tumor, which was subjected to ultrasound‐guided fine‐needle aspiration cytology (FNAC) with a provisional diagnosis of malignant lymphoma. However, after reviewing the existing results, a repeat biopsy was deemed necessary and this was performed endoluminally via gastroduodenoscopy in view of the close proximity of the tumor and the third part of the duodenum. The first biopsy failed to detect any abnormal cells, but a repeat biopsy with supporting evidence from other laboratory results led to a final diagnosis of extragonadal germ cell tumor (GCT) with duodenal infiltration.
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spelling doaj.art-93ae67a6b67d4b8887295a91c404e6e82022-12-22T00:04:35ZengWileyJGH Open2397-90702022-02-016215215410.1002/jgh3.12711Retroperitoneal extragonadal germ cell tumor with duodenal infiltration: A challenging endo‐luminal tissue diagnosisChoon‐Seng Qua0Kaik‐Boo Peh1Saravannan Kannan2Khean‐Lee Goh3Department of Gastroenterology, Mahkota Medical Centre Melaka MalaysiaDepartment of Pathology, Mahkota Medical Centre Melaka MalaysiaDepartment of Radiology, Mahkota Medical Centre Melaka MalaysiaFaculty of Medicine, University of Malaya Kuala Lumpur MalaysiaAbstract A 32‐year‐old Malay male was referred to our hospital for a second opinion. An abdominal and pelvic CT scan at the previous medical facility showed a large retroperitoneal tumor, which was subjected to ultrasound‐guided fine‐needle aspiration cytology (FNAC) with a provisional diagnosis of malignant lymphoma. However, after reviewing the existing results, a repeat biopsy was deemed necessary and this was performed endoluminally via gastroduodenoscopy in view of the close proximity of the tumor and the third part of the duodenum. The first biopsy failed to detect any abnormal cells, but a repeat biopsy with supporting evidence from other laboratory results led to a final diagnosis of extragonadal germ cell tumor (GCT) with duodenal infiltration.https://doi.org/10.1002/jgh3.12711germ cell tumorretroperitoneal tumorultrasound‐guided fine‐needle aspiration cytology
spellingShingle Choon‐Seng Qua
Kaik‐Boo Peh
Saravannan Kannan
Khean‐Lee Goh
Retroperitoneal extragonadal germ cell tumor with duodenal infiltration: A challenging endo‐luminal tissue diagnosis
JGH Open
germ cell tumor
retroperitoneal tumor
ultrasound‐guided fine‐needle aspiration cytology
title Retroperitoneal extragonadal germ cell tumor with duodenal infiltration: A challenging endo‐luminal tissue diagnosis
title_full Retroperitoneal extragonadal germ cell tumor with duodenal infiltration: A challenging endo‐luminal tissue diagnosis
title_fullStr Retroperitoneal extragonadal germ cell tumor with duodenal infiltration: A challenging endo‐luminal tissue diagnosis
title_full_unstemmed Retroperitoneal extragonadal germ cell tumor with duodenal infiltration: A challenging endo‐luminal tissue diagnosis
title_short Retroperitoneal extragonadal germ cell tumor with duodenal infiltration: A challenging endo‐luminal tissue diagnosis
title_sort retroperitoneal extragonadal germ cell tumor with duodenal infiltration a challenging endo luminal tissue diagnosis
topic germ cell tumor
retroperitoneal tumor
ultrasound‐guided fine‐needle aspiration cytology
url https://doi.org/10.1002/jgh3.12711
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