The effect of ocular biometric factors on the accuracy of various IOL power calculation formulas
Abstract Background To evaluate how differences in ocular biometry affects the Hoffer Q, Holladay 1, SRK/T, and Haigis intraocular lens power calculation formulae predictions. Methods This study was performed on 91 eyes of 91 patients who underwent uneventful cataract surgery. Ocular biometry values...
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| Format: | Article |
| Language: | English |
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BMC
2017-05-01
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| Series: | BMC Ophthalmology |
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| Online Access: | http://link.springer.com/article/10.1186/s12886-017-0454-y |
| _version_ | 1819162668362104832 |
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| author | Jinho Jeong Han Song Jimmy K. Lee Roy S. Chuck Ji-Won Kwon |
| author_facet | Jinho Jeong Han Song Jimmy K. Lee Roy S. Chuck Ji-Won Kwon |
| author_sort | Jinho Jeong |
| collection | DOAJ |
| description | Abstract Background To evaluate how differences in ocular biometry affects the Hoffer Q, Holladay 1, SRK/T, and Haigis intraocular lens power calculation formulae predictions. Methods This study was performed on 91 eyes of 91 patients who underwent uneventful cataract surgery. Ocular biometry values were measured using the IOL Master 500, and intraocular lens (IOL) power was calculated using the Haigis, Hoffer Q, Holladay 1, and SRK/T formulas. We calculated the expected difference (ED) of each 3rd generation formula from the Haigis formula by subtracting the predicted refraction of the Haigis formula from the predicted refraction of each 3rd generation formula. Post-operative anterior chamber depth (ACD) was measured at 1 month after surgery using the IOL master. We calculated errors of each formula by subtracting predicted from manifest refraction at post-operative 1 month. Correlation analysis was performed between ocular biometry values, formula expectation values, formula errors and absolute formula errors. Results Multiple regression analysis revealed that preoperative ACD was the only significant factor for ED prediction in all of the 3rd generation formulas. For mean errors, axial length and post-operative 1-month change of ACD (delta ACD) correlated significantly with the errors in all 3rd generation formulas, but not with errors of the Haigis formula. Median absolute error (MedAE) of the formulas were 0.40 D for the Hoffer Q formula, 0.37 D for the Holladay formula, 0.34 D for the SRK/T formula, and 0.41 D for the Haigis formula. The MAE of the formulas were 0.50 ± 0.47 D for the Hoffer Q formula, 0.50 ± 0.50 D for the Holladay formula, 0.47 ± 0.51 D for the SRK/T formula, and 0.50 ± 0.47 D for the Haigis formula. Conclusion Regarding ED between the third generation and Haigis formulas, preoperative ACD demonstrated the greatest influence. Calculating mean absolute errors of the formulas, all IOL formulas showed excellent and comparable accuracy. Post-operative change (delta) of ACD correlated significantly with errors of third generation formulas according to simulated ACD. |
| first_indexed | 2024-12-22T17:31:54Z |
| format | Article |
| id | doaj.art-93b1333df8bb4ae2b1ee9b36014d0576 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-22T17:31:54Z |
| publishDate | 2017-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-93b1333df8bb4ae2b1ee9b36014d05762022-12-21T18:18:36ZengBMCBMC Ophthalmology1471-24152017-05-011711710.1186/s12886-017-0454-yThe effect of ocular biometric factors on the accuracy of various IOL power calculation formulasJinho Jeong0Han Song1Jimmy K. Lee2Roy S. Chuck3Ji-Won Kwon4Department of Ophthalmology, Jeju National University College of MedicineDepartment of Ophthalmology, Myongji Hospital Seonam University College of MedicineDepartment of Ophthalmology and Visual Sciences, Montefiore Medical Center, Albert Einstein College of MedicineDepartment of Ophthalmology and Visual Sciences, Montefiore Medical Center, Albert Einstein College of MedicineDepartment of Ophthalmology, Myongji Hospital Seonam University College of MedicineAbstract Background To evaluate how differences in ocular biometry affects the Hoffer Q, Holladay 1, SRK/T, and Haigis intraocular lens power calculation formulae predictions. Methods This study was performed on 91 eyes of 91 patients who underwent uneventful cataract surgery. Ocular biometry values were measured using the IOL Master 500, and intraocular lens (IOL) power was calculated using the Haigis, Hoffer Q, Holladay 1, and SRK/T formulas. We calculated the expected difference (ED) of each 3rd generation formula from the Haigis formula by subtracting the predicted refraction of the Haigis formula from the predicted refraction of each 3rd generation formula. Post-operative anterior chamber depth (ACD) was measured at 1 month after surgery using the IOL master. We calculated errors of each formula by subtracting predicted from manifest refraction at post-operative 1 month. Correlation analysis was performed between ocular biometry values, formula expectation values, formula errors and absolute formula errors. Results Multiple regression analysis revealed that preoperative ACD was the only significant factor for ED prediction in all of the 3rd generation formulas. For mean errors, axial length and post-operative 1-month change of ACD (delta ACD) correlated significantly with the errors in all 3rd generation formulas, but not with errors of the Haigis formula. Median absolute error (MedAE) of the formulas were 0.40 D for the Hoffer Q formula, 0.37 D for the Holladay formula, 0.34 D for the SRK/T formula, and 0.41 D for the Haigis formula. The MAE of the formulas were 0.50 ± 0.47 D for the Hoffer Q formula, 0.50 ± 0.50 D for the Holladay formula, 0.47 ± 0.51 D for the SRK/T formula, and 0.50 ± 0.47 D for the Haigis formula. Conclusion Regarding ED between the third generation and Haigis formulas, preoperative ACD demonstrated the greatest influence. Calculating mean absolute errors of the formulas, all IOL formulas showed excellent and comparable accuracy. Post-operative change (delta) of ACD correlated significantly with errors of third generation formulas according to simulated ACD.http://link.springer.com/article/10.1186/s12886-017-0454-yAnterior chamber depthIOL formulaOcular biometry |
| spellingShingle | Jinho Jeong Han Song Jimmy K. Lee Roy S. Chuck Ji-Won Kwon The effect of ocular biometric factors on the accuracy of various IOL power calculation formulas BMC Ophthalmology Anterior chamber depth IOL formula Ocular biometry |
| title | The effect of ocular biometric factors on the accuracy of various IOL power calculation formulas |
| title_full | The effect of ocular biometric factors on the accuracy of various IOL power calculation formulas |
| title_fullStr | The effect of ocular biometric factors on the accuracy of various IOL power calculation formulas |
| title_full_unstemmed | The effect of ocular biometric factors on the accuracy of various IOL power calculation formulas |
| title_short | The effect of ocular biometric factors on the accuracy of various IOL power calculation formulas |
| title_sort | effect of ocular biometric factors on the accuracy of various iol power calculation formulas |
| topic | Anterior chamber depth IOL formula Ocular biometry |
| url | http://link.springer.com/article/10.1186/s12886-017-0454-y |
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