The Patient with Difficult Cancer Pain
Most patients with cancer pain can be managed with relatively simple methods using oral analgesics at relatively low doses, even for prolonged periods of time. However, in some clinical conditions pain may be more difficult to manage. Various factors can interfere with a desirable and favorable anal...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-04-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/11/4/565 |
| _version_ | 1797708951247126528 |
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| author | Sebastiano Mercadante |
| author_facet | Sebastiano Mercadante |
| author_sort | Sebastiano Mercadante |
| collection | DOAJ |
| description | Most patients with cancer pain can be managed with relatively simple methods using oral analgesics at relatively low doses, even for prolonged periods of time. However, in some clinical conditions pain may be more difficult to manage. Various factors can interfere with a desirable and favorable analgesic response. Data from several studies assessing factors of negative pain prognosis have indicated that neuropathic pain, incident pain, psychological distress, opioid addiction, and baseline pain intensity were associated with more difficult pain control. In this narrative review, the main factors that make the therapeutic response to opioids difficult are examined. |
| first_indexed | 2024-03-12T06:30:14Z |
| format | Article |
| id | doaj.art-93b48c904c12497db0cb44be9a86237d |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-12T06:30:14Z |
| publishDate | 2019-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-93b48c904c12497db0cb44be9a86237d2023-09-03T01:40:57ZengMDPI AGCancers2072-66942019-04-0111456510.3390/cancers11040565cancers11040565The Patient with Difficult Cancer PainSebastiano Mercadante0Main regional center for pain relief and supportive/palliative care, La Maddalena Cancer center, via San Lorenzo 319, 290146 Palermo, ItalyMost patients with cancer pain can be managed with relatively simple methods using oral analgesics at relatively low doses, even for prolonged periods of time. However, in some clinical conditions pain may be more difficult to manage. Various factors can interfere with a desirable and favorable analgesic response. Data from several studies assessing factors of negative pain prognosis have indicated that neuropathic pain, incident pain, psychological distress, opioid addiction, and baseline pain intensity were associated with more difficult pain control. In this narrative review, the main factors that make the therapeutic response to opioids difficult are examined.https://www.mdpi.com/2072-6694/11/4/565cancer painopioidsneuropathic painincident paincognitive disturbanceaddictionpsychological factors |
| spellingShingle | Sebastiano Mercadante The Patient with Difficult Cancer Pain Cancers cancer pain opioids neuropathic pain incident pain cognitive disturbance addiction psychological factors |
| title | The Patient with Difficult Cancer Pain |
| title_full | The Patient with Difficult Cancer Pain |
| title_fullStr | The Patient with Difficult Cancer Pain |
| title_full_unstemmed | The Patient with Difficult Cancer Pain |
| title_short | The Patient with Difficult Cancer Pain |
| title_sort | patient with difficult cancer pain |
| topic | cancer pain opioids neuropathic pain incident pain cognitive disturbance addiction psychological factors |
| url | https://www.mdpi.com/2072-6694/11/4/565 |
| work_keys_str_mv | AT sebastianomercadante thepatientwithdifficultcancerpain AT sebastianomercadante patientwithdifficultcancerpain |