Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes
Bioorthogonal diversification of peptides is generally dependent on impractical prefunctionalization methods. Here, the authors develop a manganese(I)-catalyzed C–H fluorescent labeling with BODIPY probes, which enables the development of activatable fluorophores to image cell function.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-23462-9 |
| _version_ | 1818735766858104832 |
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| author | Nikolaos Kaplaneris Jongwoo Son Lorena Mendive-Tapia Adelina Kopp Nicole D. Barth Isaac Maksso Marc Vendrell Lutz Ackermann |
| author_facet | Nikolaos Kaplaneris Jongwoo Son Lorena Mendive-Tapia Adelina Kopp Nicole D. Barth Isaac Maksso Marc Vendrell Lutz Ackermann |
| author_sort | Nikolaos Kaplaneris |
| collection | DOAJ |
| description | Bioorthogonal diversification of peptides is generally dependent on impractical prefunctionalization methods. Here, the authors develop a manganese(I)-catalyzed C–H fluorescent labeling with BODIPY probes, which enables the development of activatable fluorophores to image cell function. |
| first_indexed | 2024-12-18T00:26:29Z |
| format | Article |
| id | doaj.art-93b52903be4747fead66811972b504c1 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T00:26:29Z |
| publishDate | 2021-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-93b52903be4747fead66811972b504c12022-12-21T21:27:15ZengNature PortfolioNature Communications2041-17232021-06-011211910.1038/s41467-021-23462-9Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probesNikolaos Kaplaneris0Jongwoo Son1Lorena Mendive-Tapia2Adelina Kopp3Nicole D. Barth4Isaac Maksso5Marc Vendrell6Lutz Ackermann7Institut für Organische und Biomolekulare Chemie, Georg-August-Universität GöttingenInstitut für Organische und Biomolekulare Chemie, Georg-August-Universität GöttingenCentre for Inflammation Research, The University of EdinburghInstitut für Organische und Biomolekulare Chemie, Georg-August-Universität GöttingenCentre for Inflammation Research, The University of EdinburghInstitut für Organische und Biomolekulare Chemie, Georg-August-Universität GöttingenCentre for Inflammation Research, The University of EdinburghInstitut für Organische und Biomolekulare Chemie, Georg-August-Universität GöttingenBioorthogonal diversification of peptides is generally dependent on impractical prefunctionalization methods. Here, the authors develop a manganese(I)-catalyzed C–H fluorescent labeling with BODIPY probes, which enables the development of activatable fluorophores to image cell function.https://doi.org/10.1038/s41467-021-23462-9 |
| spellingShingle | Nikolaos Kaplaneris Jongwoo Son Lorena Mendive-Tapia Adelina Kopp Nicole D. Barth Isaac Maksso Marc Vendrell Lutz Ackermann Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes Nature Communications |
| title | Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
| title_full | Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
| title_fullStr | Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
| title_full_unstemmed | Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
| title_short | Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
| title_sort | chemodivergent manganese catalyzed c h activation modular synthesis of fluorogenic probes |
| url | https://doi.org/10.1038/s41467-021-23462-9 |
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