Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes
Bioorthogonal diversification of peptides is generally dependent on impractical prefunctionalization methods. Here, the authors develop a manganese(I)-catalyzed C–H fluorescent labeling with BODIPY probes, which enables the development of activatable fluorophores to image cell function.
Main Authors: | Nikolaos Kaplaneris, Jongwoo Son, Lorena Mendive-Tapia, Adelina Kopp, Nicole D. Barth, Isaac Maksso, Marc Vendrell, Lutz Ackermann |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-23462-9 |
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