Renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2-month-old infant: a case report

Here, we present the case of a 2-month-old male infant with hyponatremic hypertensive syndrome resulting from stenosis of the right proximal and mid-renal arteries. The patient exhibited nephrotic-range proteinuria, low serum albumin, increased serum creatinine, and elevated renin and aldosterone le...

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Main Authors: Dabin Kim, Yo Han Ahn, Hee Gyung Kang, Ji Hyun Kim, Seon Hee Lim
Format: Article
Language:English
Published: Korean Society of Pediatric Nephrology 2023-12-01
Series:Childhood Kidney Diseases
Subjects:
Online Access:http://chikd.org/upload/pdf/ckd-23-017.pdf
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author Dabin Kim
Yo Han Ahn
Hee Gyung Kang
Ji Hyun Kim
Seon Hee Lim
author_facet Dabin Kim
Yo Han Ahn
Hee Gyung Kang
Ji Hyun Kim
Seon Hee Lim
author_sort Dabin Kim
collection DOAJ
description Here, we present the case of a 2-month-old male infant with hyponatremic hypertensive syndrome resulting from stenosis of the right proximal and mid-renal arteries. The patient exhibited nephrotic-range proteinuria, low serum albumin, increased serum creatinine, and elevated renin and aldosterone levels. Doppler ultrasonography and computed tomography angiography revealed decreased vascular flow in the small right renal artery. Following a successful percutaneous balloon angioplasty, the patient experienced a decrease in blood pressure and normalization of serum electrolyte levels within a few days. However, it took 3 months for the proteinuria to resolve completely. This case is significant as it represents the first reported instance of a neonate presenting with clinical features resembling congenital nephrotic syndrome caused by renal artery stenosis that was successfully treated with percutaneous renal angioplasty.
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spelling doaj.art-93b6ed884d044871b106d0c96b31b2602024-02-14T07:01:36ZengKorean Society of Pediatric NephrologyChildhood Kidney Diseases2384-02422384-02502023-12-0127211712010.3339/ckd.23.017792Renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2-month-old infant: a case reportDabin Kim0Yo Han Ahn1Hee Gyung Kang2Ji Hyun Kim3Seon Hee Lim4 Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea Department of Pediatrics, Pusan National University Children’s Hospital, Pusan National University School of Medicine, Yangsan, Republic of KoreaHere, we present the case of a 2-month-old male infant with hyponatremic hypertensive syndrome resulting from stenosis of the right proximal and mid-renal arteries. The patient exhibited nephrotic-range proteinuria, low serum albumin, increased serum creatinine, and elevated renin and aldosterone levels. Doppler ultrasonography and computed tomography angiography revealed decreased vascular flow in the small right renal artery. Following a successful percutaneous balloon angioplasty, the patient experienced a decrease in blood pressure and normalization of serum electrolyte levels within a few days. However, it took 3 months for the proteinuria to resolve completely. This case is significant as it represents the first reported instance of a neonate presenting with clinical features resembling congenital nephrotic syndrome caused by renal artery stenosis that was successfully treated with percutaneous renal angioplasty.http://chikd.org/upload/pdf/ckd-23-017.pdfcase reportscongenitalhypertensionhyponatremianephrotic syndromerenal artery stenosis
spellingShingle Dabin Kim
Yo Han Ahn
Hee Gyung Kang
Ji Hyun Kim
Seon Hee Lim
Renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2-month-old infant: a case report
Childhood Kidney Diseases
case reports
congenital
hypertension
hyponatremia
nephrotic syndrome
renal artery stenosis
title Renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2-month-old infant: a case report
title_full Renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2-month-old infant: a case report
title_fullStr Renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2-month-old infant: a case report
title_full_unstemmed Renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2-month-old infant: a case report
title_short Renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2-month-old infant: a case report
title_sort renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2 month old infant a case report
topic case reports
congenital
hypertension
hyponatremia
nephrotic syndrome
renal artery stenosis
url http://chikd.org/upload/pdf/ckd-23-017.pdf
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