Usefulness of physiological coronary assessment with iFR in daily practice and all-comer patients: immediate and follow-up results

ABSTRACT Introduction and objectives: The objective of this study was to describe our experience with coronary physiology assessment using the instantaneous wave-free ratio (iFR) and/or a Syncvision-guided iFR-pullback study [Syncvision version 4.1.0.5, Philips Volcano, Belgium] in all-comer patient...

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Main Authors: Cristina Pericet-Rodríguez, Francisco José Hidalgo-Lesmes, Rafael González-Manzanares, Soledad Ojeda-Pineda, Aurora Luque-Moreno, Javier Suárez de Lezo, Miguel Ángel Romero-Moreno, Francisco Mazuelos-Bellido, José María Segura Saint-Gerons, Ana Fernández-Ruiz, María Guisela Flores-Vergara, Manuel Pan Álvarez-Ossorio
Format: Article
Language:English
Published: Permanyer 2021-08-01
Series:REC: Interventional Cardiology (English Ed.)
Subjects:
Online Access:https://recintervcardiol.org/en/index.php?option=com_content&view=article&id=627
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author Cristina Pericet-Rodríguez
Francisco José Hidalgo-Lesmes
Rafael González-Manzanares
Soledad Ojeda-Pineda
Aurora Luque-Moreno
Javier Suárez de Lezo
Miguel Ángel Romero-Moreno
Francisco Mazuelos-Bellido
José María Segura Saint-Gerons
Ana Fernández-Ruiz
María Guisela Flores-Vergara
Manuel Pan Álvarez-Ossorio
author_facet Cristina Pericet-Rodríguez
Francisco José Hidalgo-Lesmes
Rafael González-Manzanares
Soledad Ojeda-Pineda
Aurora Luque-Moreno
Javier Suárez de Lezo
Miguel Ángel Romero-Moreno
Francisco Mazuelos-Bellido
José María Segura Saint-Gerons
Ana Fernández-Ruiz
María Guisela Flores-Vergara
Manuel Pan Álvarez-Ossorio
author_sort Cristina Pericet-Rodríguez
collection DOAJ
description ABSTRACT Introduction and objectives: The objective of this study was to describe our experience with coronary physiology assessment using the instantaneous wave-free ratio (iFR) and/or a Syncvision-guided iFR-pullback study [Syncvision version 4.1.0.5, Philips Volcano, Belgium] in all-comer patients. Methods: Consecutive patients undergoing coronary physiology assessment with the iFR (and/or a Syncvision-guided iFR-pullback study) at our center between January 2017 and December 2019 were included. The iFR cut-off value was 0.89. The primary endpoint was a composite of cardiac death, myocardial infarction, probable or definitive stent thrombosis, and target lesion revascularization. Results: A total of 277 patients with 433 lesions evaluated were included. The mean age was 65 ± 10 years and 74% were men. Personal history of diabetes mellitus was present in 41% of patients. Clinical presentation was stable angina in 160 patients (58%), and acute coronary syndrome in 117 patients (42%). iFRs > 0.89 were obtained in 266 lesions (61.4%) on which the PCI was postponed. The remaining lesions were revascularized. The Syncvision software was used to guide the iFR-pullback study in 155 lesions (36%) and the decision-making process, mainly in long, diffuse or sequential lesions (91 lesions, 58.7%), and intermediate lesions (52 lesions, 33.5%). After a median follow-up of 18 months, the primary endpoint occurred in 17 patients (6.1%) without differences regarding the baseline iFR (≤ 0.89 or > 0.89) (4.2% vs 3.8%; P = .9) or the clinical presentation (stable angina or acute coronary syndrome) (4.4% vs 8.5%; P = .1) Conclusions: The use of coronary physiology assessment with the iFR and the Syncvision-guided iFR-pullback study in the routine daily practice and in all-comer patients seems safe with a low percentage of major adverse cardiovascular events at the mid-term follow-up.
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spelling doaj.art-93b861057e9745f2bf75369db8b7e8432022-12-21T22:05:42ZengPermanyerREC: Interventional Cardiology (English Ed.)2604-73222021-08-013318218910.24875/RECICE.M21000206Usefulness of physiological coronary assessment with iFR in daily practice and all-comer patients: immediate and follow-up resultsCristina Pericet-Rodríguez0Francisco José Hidalgo-Lesmes1Rafael González-Manzanares2Soledad Ojeda-Pineda3Aurora Luque-Moreno4Javier Suárez de Lezo5Miguel Ángel Romero-Moreno6Francisco Mazuelos-Bellido7José María Segura Saint-Gerons8Ana Fernández-Ruiz9María Guisela Flores-Vergara10Manuel Pan Álvarez-Ossorio11Servicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainServicio de Cardiología, Hospital Universitario Reina Sofía, Universidad de Córdoba. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, SpainABSTRACT Introduction and objectives: The objective of this study was to describe our experience with coronary physiology assessment using the instantaneous wave-free ratio (iFR) and/or a Syncvision-guided iFR-pullback study [Syncvision version 4.1.0.5, Philips Volcano, Belgium] in all-comer patients. Methods: Consecutive patients undergoing coronary physiology assessment with the iFR (and/or a Syncvision-guided iFR-pullback study) at our center between January 2017 and December 2019 were included. The iFR cut-off value was 0.89. The primary endpoint was a composite of cardiac death, myocardial infarction, probable or definitive stent thrombosis, and target lesion revascularization. Results: A total of 277 patients with 433 lesions evaluated were included. The mean age was 65 ± 10 years and 74% were men. Personal history of diabetes mellitus was present in 41% of patients. Clinical presentation was stable angina in 160 patients (58%), and acute coronary syndrome in 117 patients (42%). iFRs > 0.89 were obtained in 266 lesions (61.4%) on which the PCI was postponed. The remaining lesions were revascularized. The Syncvision software was used to guide the iFR-pullback study in 155 lesions (36%) and the decision-making process, mainly in long, diffuse or sequential lesions (91 lesions, 58.7%), and intermediate lesions (52 lesions, 33.5%). After a median follow-up of 18 months, the primary endpoint occurred in 17 patients (6.1%) without differences regarding the baseline iFR (≤ 0.89 or > 0.89) (4.2% vs 3.8%; P = .9) or the clinical presentation (stable angina or acute coronary syndrome) (4.4% vs 8.5%; P = .1) Conclusions: The use of coronary physiology assessment with the iFR and the Syncvision-guided iFR-pullback study in the routine daily practice and in all-comer patients seems safe with a low percentage of major adverse cardiovascular events at the mid-term follow-up.https://recintervcardiol.org/en/index.php?option=com_content&view=article&id=627Physiological assessment All-comer patients Syncvision-guided iFR-pullback study
spellingShingle Cristina Pericet-Rodríguez
Francisco José Hidalgo-Lesmes
Rafael González-Manzanares
Soledad Ojeda-Pineda
Aurora Luque-Moreno
Javier Suárez de Lezo
Miguel Ángel Romero-Moreno
Francisco Mazuelos-Bellido
José María Segura Saint-Gerons
Ana Fernández-Ruiz
María Guisela Flores-Vergara
Manuel Pan Álvarez-Ossorio
Usefulness of physiological coronary assessment with iFR in daily practice and all-comer patients: immediate and follow-up results
REC: Interventional Cardiology (English Ed.)
Physiological assessment
All-comer patients
Syncvision-guided iFR-pullback study
title Usefulness of physiological coronary assessment with iFR in daily practice and all-comer patients: immediate and follow-up results
title_full Usefulness of physiological coronary assessment with iFR in daily practice and all-comer patients: immediate and follow-up results
title_fullStr Usefulness of physiological coronary assessment with iFR in daily practice and all-comer patients: immediate and follow-up results
title_full_unstemmed Usefulness of physiological coronary assessment with iFR in daily practice and all-comer patients: immediate and follow-up results
title_short Usefulness of physiological coronary assessment with iFR in daily practice and all-comer patients: immediate and follow-up results
title_sort usefulness of physiological coronary assessment with ifr in daily practice and all comer patients immediate and follow up results
topic Physiological assessment
All-comer patients
Syncvision-guided iFR-pullback study
url https://recintervcardiol.org/en/index.php?option=com_content&view=article&id=627
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