Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report
<p>Abstract</p> <p>Background</p> <p>Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin is a rare but serious complication of the use of Nitrofurantoin.</p> <p>Case presentation</p> <p>A 72 year old woman taking Nitrofurantoin...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-08-01
|
| Series: | Journal of Medical Case Reports |
| Online Access: | http://www.jmedicalcasereports.com/content/1/1/59 |
| _version_ | 1811312253893345280 |
|---|---|
| author | Peall Adrian F Hodges Aidan |
| author_facet | Peall Adrian F Hodges Aidan |
| author_sort | Peall Adrian F |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin is a rare but serious complication of the use of Nitrofurantoin.</p> <p>Case presentation</p> <p>A 72 year old woman taking Nitrofurantoin for recurrent urinary sepsis presenting with breathlessness abdominal discomfort and abnormal liver function tests is described. Drug toxicity secondary to Nitrofurantoin was diagnosed. Cessation of the drug and a course of steroids markedly improved her condition.</p> <p>Discussion</p> <p>We review the drug reactions associated with Nitrofurantoin and suggest an alternative treatment strategy for recurrent urinary sepsis.</p> <p>Conclusion</p> <p>Adverse drug reactions are an important cause of concomitant lung and liver toxicity and the mainstay of treatment is drug withdrawal.</p> |
| first_indexed | 2024-04-13T10:32:49Z |
| format | Article |
| id | doaj.art-93b86e5567814e6f891abafc2bab798d |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-04-13T10:32:49Z |
| publishDate | 2007-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-93b86e5567814e6f891abafc2bab798d2022-12-22T02:50:08ZengBMCJournal of Medical Case Reports1752-19472007-08-01115910.1186/1752-1947-1-59Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case reportPeall Adrian FHodges Aidan<p>Abstract</p> <p>Background</p> <p>Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin is a rare but serious complication of the use of Nitrofurantoin.</p> <p>Case presentation</p> <p>A 72 year old woman taking Nitrofurantoin for recurrent urinary sepsis presenting with breathlessness abdominal discomfort and abnormal liver function tests is described. Drug toxicity secondary to Nitrofurantoin was diagnosed. Cessation of the drug and a course of steroids markedly improved her condition.</p> <p>Discussion</p> <p>We review the drug reactions associated with Nitrofurantoin and suggest an alternative treatment strategy for recurrent urinary sepsis.</p> <p>Conclusion</p> <p>Adverse drug reactions are an important cause of concomitant lung and liver toxicity and the mainstay of treatment is drug withdrawal.</p>http://www.jmedicalcasereports.com/content/1/1/59 |
| spellingShingle | Peall Adrian F Hodges Aidan Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report Journal of Medical Case Reports |
| title | Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report |
| title_full | Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report |
| title_fullStr | Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report |
| title_full_unstemmed | Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report |
| title_short | Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report |
| title_sort | concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin a case report |
| url | http://www.jmedicalcasereports.com/content/1/1/59 |
| work_keys_str_mv | AT pealladrianf concomitantpulmonaryandhepatictoxicitysecondarytonitrofurantoinacasereport AT hodgesaidan concomitantpulmonaryandhepatictoxicitysecondarytonitrofurantoinacasereport |