USP7 Induces Chemoresistance in Triple-Negative Breast Cancer via Deubiquitination and Stabilization of ABCB1

USP7 Induces Chemoresistance in Triple-Negative Breast Cancer via Deubiquitination and Stabilization of ABCB1

Triple-negative breast cancer (TNBC) accounts for 15–20% of all breast cancer. TNBC does not express the estrogen receptor, progesterone receptor, or human epidermal growth factor receptor 2. Cytotoxic chemotherapy and surgery are the current therapeutic strategies for TNBC patients, but the chemore...

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Bibliographic Details
Main Authors: Yueh-Te Lin, Joseph Lin, Yi-En Liu, Yun-Cen Chen, Shiang-Ting Liu, Kai-Wen Hsu, Dar-Ren Chen, Han-Tsang Wu
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
ubiquitin specific protease 7
chemoresistance
triple-negative breast cancer
ATP-binding cassette B1
Online Access:https://www.mdpi.com/2073-4409/11/20/3294

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