Determination of the role of DDX3 a factor involved in mammalian RNAi pathway using an shRNA-expression library.

Determination of the role of DDX3 a factor involved in mammalian RNAi pathway using an shRNA-expression library.

RNA interference (RNAi) is an endogenous RNA-destruction phenomenon induced by certain double-stranded RNAs (dsRNAs). In RNAi, dsRNAs are processed into small interfering RNAs (siRNAs) which in turn trigger the cleavage of the target mRNA. Here, using a short hairpin RNA-expression library, we ident...

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Bibliographic Details
Main Authors: Vivi Kasim, Shourong Wu, Kazunari Taira, Makoto Miyagishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3602433?pdf=render

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