Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease
This study aims to determine how nutrition therapy with brown rice, tuna fish, pineapple, and cucumber affects proteinuria and albuminuria in male Wistar rats with chronic kidney disease (CKD). In this study, 16 male Wistar rats with CKD were divided into four groups. The result states that the thi...
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PAGEPress Publications
2024-03-01
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Online Access: | https://www.pagepressjournals.org/index.php/jbr/article/view/11883 |
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author | Tasnim Tasnim Selpirahmawati Saranani |
author_facet | Tasnim Tasnim Selpirahmawati Saranani |
author_sort | Tasnim Tasnim |
collection | DOAJ |
description |
This study aims to determine how nutrition therapy with brown rice, tuna fish, pineapple, and cucumber affects proteinuria and albuminuria in male Wistar rats with chronic kidney disease (CKD). In this study, 16 male Wistar rats with CKD were divided into four groups. The result states that the third treatment, consisting of 341 g/kg BW (Body Weight)/day brown rice, 15 g/kg BW/day tuna fish, 2 g/kg BW/day pineapple, and 2 g/kg BW/day cucumber could reduce both proteinuria (p < 0.01) and albuminuria (p < 0.01) in rats. However, the first (250 g brown rice, 13 g/kg BW/day tuna fish, 1 g/kg BW/day pineapple, 1 g/kg BW/day cucumber) and second treatment (296 g/kg BW/day brown rice, 14 g/kg BW/day tuna fish, 1.5 g/kg BW/day pineapple, 1.5 g/kg BW/day cucumber) could not reduce the levels of proteinuria and albuminuria in rats. In conclusion, giving a balanced diet containing 341 g/kg BW/day of brown rice, 15 g/kg BW/day of tuna fish, 2 g/kg BW/day of pineapple, and 2 g/kg BW/day of cucumber for CKD can maintain body fluid and increase the re-absorption of proteins and albumin. Therefore, the third nutrition formula can be recommended to people with kidney disease after clinical tests on humans.
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first_indexed | 2024-04-25T01:44:28Z |
format | Article |
id | doaj.art-93bc0a783dea4c4cb964a9800076dee6 |
institution | Directory Open Access Journal |
issn | 1826-8838 2284-0230 |
language | English |
last_indexed | 2024-04-25T01:44:28Z |
publishDate | 2024-03-01 |
publisher | PAGEPress Publications |
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series | Journal of Biological Research |
spelling | doaj.art-93bc0a783dea4c4cb964a9800076dee62024-03-07T23:12:17ZengPAGEPress PublicationsJournal of Biological Research1826-88382284-02302024-03-0110.4081/jbr.2024.11883Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney diseaseTasnim Tasnim0Selpirahmawati Saranani1Department of Public Health, Mandala Waluya UniversityDepartment of Pharmacy, Mandala Waluya University This study aims to determine how nutrition therapy with brown rice, tuna fish, pineapple, and cucumber affects proteinuria and albuminuria in male Wistar rats with chronic kidney disease (CKD). In this study, 16 male Wistar rats with CKD were divided into four groups. The result states that the third treatment, consisting of 341 g/kg BW (Body Weight)/day brown rice, 15 g/kg BW/day tuna fish, 2 g/kg BW/day pineapple, and 2 g/kg BW/day cucumber could reduce both proteinuria (p < 0.01) and albuminuria (p < 0.01) in rats. However, the first (250 g brown rice, 13 g/kg BW/day tuna fish, 1 g/kg BW/day pineapple, 1 g/kg BW/day cucumber) and second treatment (296 g/kg BW/day brown rice, 14 g/kg BW/day tuna fish, 1.5 g/kg BW/day pineapple, 1.5 g/kg BW/day cucumber) could not reduce the levels of proteinuria and albuminuria in rats. In conclusion, giving a balanced diet containing 341 g/kg BW/day of brown rice, 15 g/kg BW/day of tuna fish, 2 g/kg BW/day of pineapple, and 2 g/kg BW/day of cucumber for CKD can maintain body fluid and increase the re-absorption of proteins and albumin. Therefore, the third nutrition formula can be recommended to people with kidney disease after clinical tests on humans. https://www.pagepressjournals.org/index.php/jbr/article/view/11883Chronic kidney diseasenutrition therapyproteinsalbumins |
spellingShingle | Tasnim Tasnim Selpirahmawati Saranani Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease Journal of Biological Research Chronic kidney disease nutrition therapy proteins albumins |
title | Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease |
title_full | Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease |
title_fullStr | Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease |
title_full_unstemmed | Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease |
title_short | Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease |
title_sort | analysis of the effect of brown rice tuna cucumber and pineapple treatment on proteinuria and albuminuria in wistar rats strain with chronic kidney disease |
topic | Chronic kidney disease nutrition therapy proteins albumins |
url | https://www.pagepressjournals.org/index.php/jbr/article/view/11883 |
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