Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease

This study aims to determine how nutrition therapy with brown rice, tuna fish, pineapple, and cucumber affects proteinuria and albuminuria in male Wistar rats with chronic kidney disease (CKD). In this study, 16 male Wistar rats with CKD were divided into four groups. The result states that the thi...

Full description

Bibliographic Details
Main Authors: Tasnim Tasnim, Selpirahmawati Saranani
Format: Article
Language:English
Published: PAGEPress Publications 2024-03-01
Series:Journal of Biological Research
Subjects:
Online Access:https://www.pagepressjournals.org/index.php/jbr/article/view/11883
_version_ 1797269192607531008
author Tasnim Tasnim
Selpirahmawati Saranani
author_facet Tasnim Tasnim
Selpirahmawati Saranani
author_sort Tasnim Tasnim
collection DOAJ
description This study aims to determine how nutrition therapy with brown rice, tuna fish, pineapple, and cucumber affects proteinuria and albuminuria in male Wistar rats with chronic kidney disease (CKD). In this study, 16 male Wistar rats with CKD were divided into four groups. The result states that the third treatment, consisting of 341 g/kg BW (Body Weight)/day brown rice, 15 g/kg BW/day tuna fish, 2 g/kg BW/day pineapple, and 2 g/kg BW/day cucumber could reduce both proteinuria (p < 0.01) and albuminuria (p < 0.01) in rats. However, the first (250 g brown rice, 13 g/kg BW/day tuna fish, 1 g/kg BW/day pineapple, 1 g/kg BW/day cucumber) and second treatment (296 g/kg BW/day brown rice, 14 g/kg BW/day tuna fish, 1.5 g/kg BW/day pineapple, 1.5 g/kg BW/day cucumber) could not reduce the levels of proteinuria and albuminuria in rats. In conclusion, giving a balanced diet containing 341 g/kg BW/day of brown rice, 15 g/kg BW/day of tuna fish, 2 g/kg BW/day of pineapple, and 2 g/kg BW/day of cucumber for CKD can maintain body fluid and increase the re-absorption of proteins and albumin. Therefore, the third nutrition formula can be recommended to people with kidney disease after clinical tests on humans.
first_indexed 2024-04-25T01:44:28Z
format Article
id doaj.art-93bc0a783dea4c4cb964a9800076dee6
institution Directory Open Access Journal
issn 1826-8838
2284-0230
language English
last_indexed 2024-04-25T01:44:28Z
publishDate 2024-03-01
publisher PAGEPress Publications
record_format Article
series Journal of Biological Research
spelling doaj.art-93bc0a783dea4c4cb964a9800076dee62024-03-07T23:12:17ZengPAGEPress PublicationsJournal of Biological Research1826-88382284-02302024-03-0110.4081/jbr.2024.11883Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney diseaseTasnim Tasnim0Selpirahmawati Saranani1Department of Public Health, Mandala Waluya UniversityDepartment of Pharmacy, Mandala Waluya University This study aims to determine how nutrition therapy with brown rice, tuna fish, pineapple, and cucumber affects proteinuria and albuminuria in male Wistar rats with chronic kidney disease (CKD). In this study, 16 male Wistar rats with CKD were divided into four groups. The result states that the third treatment, consisting of 341 g/kg BW (Body Weight)/day brown rice, 15 g/kg BW/day tuna fish, 2 g/kg BW/day pineapple, and 2 g/kg BW/day cucumber could reduce both proteinuria (p < 0.01) and albuminuria (p < 0.01) in rats. However, the first (250 g brown rice, 13 g/kg BW/day tuna fish, 1 g/kg BW/day pineapple, 1 g/kg BW/day cucumber) and second treatment (296 g/kg BW/day brown rice, 14 g/kg BW/day tuna fish, 1.5 g/kg BW/day pineapple, 1.5 g/kg BW/day cucumber) could not reduce the levels of proteinuria and albuminuria in rats. In conclusion, giving a balanced diet containing 341 g/kg BW/day of brown rice, 15 g/kg BW/day of tuna fish, 2 g/kg BW/day of pineapple, and 2 g/kg BW/day of cucumber for CKD can maintain body fluid and increase the re-absorption of proteins and albumin. Therefore, the third nutrition formula can be recommended to people with kidney disease after clinical tests on humans. https://www.pagepressjournals.org/index.php/jbr/article/view/11883Chronic kidney diseasenutrition therapyproteinsalbumins
spellingShingle Tasnim Tasnim
Selpirahmawati Saranani
Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease
Journal of Biological Research
Chronic kidney disease
nutrition therapy
proteins
albumins
title Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease
title_full Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease
title_fullStr Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease
title_full_unstemmed Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease
title_short Analysis of the effect of brown rice, tuna, cucumber, and pineapple treatment on proteinuria and albuminuria in Wistar Rats strain with chronic kidney disease
title_sort analysis of the effect of brown rice tuna cucumber and pineapple treatment on proteinuria and albuminuria in wistar rats strain with chronic kidney disease
topic Chronic kidney disease
nutrition therapy
proteins
albumins
url https://www.pagepressjournals.org/index.php/jbr/article/view/11883
work_keys_str_mv AT tasnimtasnim analysisoftheeffectofbrownricetunacucumberandpineappletreatmentonproteinuriaandalbuminuriainwistarratsstrainwithchronickidneydisease
AT selpirahmawatisaranani analysisoftheeffectofbrownricetunacucumberandpineappletreatmentonproteinuriaandalbuminuriainwistarratsstrainwithchronickidneydisease