Microbial Fermentation Processes of Lactic Acid: Challenges, Solutions, and Future Prospects
The demand for lactic acid and lactic acid-derived products in the food, pharmaceutical, and cosmetic industries is increasing year by year. In recent decades, the synthesis of lactic acid by microbials has gained much attention from scientists due to the superior optical purity of the product, its...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/12/12/2311 |
| _version_ | 1797594811269644288 |
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| author | Yueying Huang Yu Wang Nan Shang Pinglan Li |
| author_facet | Yueying Huang Yu Wang Nan Shang Pinglan Li |
| author_sort | Yueying Huang |
| collection | DOAJ |
| description | The demand for lactic acid and lactic acid-derived products in the food, pharmaceutical, and cosmetic industries is increasing year by year. In recent decades, the synthesis of lactic acid by microbials has gained much attention from scientists due to the superior optical purity of the product, its low production costs, and its higher production efficiency compared to chemical synthesis. Microbial fermentation involves the selection of feedstock, strains, and fermentation modes. Each step can potentially affect the yield and purity of the final product. Therefore, there are still many critical challenges in lactic acid production. The costs of feedstocks and energy; the inhibition of substrates and end-product; the sensitivity to the inhibitory compounds released during pretreatment; and the lower optical purity are the main obstacles hindering the fermentation of lactic acid. This review highlights the limitations and challenges of applying microbial fermentation in lactic acid production. In addition, corresponding solutions to these difficulties are summarized in order to provide some guidance for the industrial production of lactic acid. |
| first_indexed | 2024-03-11T02:28:57Z |
| format | Article |
| id | doaj.art-93be454595044032abc117fd8bc9164b |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-11T02:28:57Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-93be454595044032abc117fd8bc9164b2023-11-18T10:23:57ZengMDPI AGFoods2304-81582023-06-011212231110.3390/foods12122311Microbial Fermentation Processes of Lactic Acid: Challenges, Solutions, and Future ProspectsYueying Huang0Yu Wang1Nan Shang2Pinglan Li3Key Laboratory of Functional Dairy, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaKey Laboratory of Functional Dairy, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Engineering, China Agricultural University, Beijing 100083, ChinaKey Laboratory of Functional Dairy, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaThe demand for lactic acid and lactic acid-derived products in the food, pharmaceutical, and cosmetic industries is increasing year by year. In recent decades, the synthesis of lactic acid by microbials has gained much attention from scientists due to the superior optical purity of the product, its low production costs, and its higher production efficiency compared to chemical synthesis. Microbial fermentation involves the selection of feedstock, strains, and fermentation modes. Each step can potentially affect the yield and purity of the final product. Therefore, there are still many critical challenges in lactic acid production. The costs of feedstocks and energy; the inhibition of substrates and end-product; the sensitivity to the inhibitory compounds released during pretreatment; and the lower optical purity are the main obstacles hindering the fermentation of lactic acid. This review highlights the limitations and challenges of applying microbial fermentation in lactic acid production. In addition, corresponding solutions to these difficulties are summarized in order to provide some guidance for the industrial production of lactic acid.https://www.mdpi.com/2304-8158/12/12/2311lactic acid productionmicrobial fermentationproduction costsdifficulties in production process |
| spellingShingle | Yueying Huang Yu Wang Nan Shang Pinglan Li Microbial Fermentation Processes of Lactic Acid: Challenges, Solutions, and Future Prospects Foods lactic acid production microbial fermentation production costs difficulties in production process |
| title | Microbial Fermentation Processes of Lactic Acid: Challenges, Solutions, and Future Prospects |
| title_full | Microbial Fermentation Processes of Lactic Acid: Challenges, Solutions, and Future Prospects |
| title_fullStr | Microbial Fermentation Processes of Lactic Acid: Challenges, Solutions, and Future Prospects |
| title_full_unstemmed | Microbial Fermentation Processes of Lactic Acid: Challenges, Solutions, and Future Prospects |
| title_short | Microbial Fermentation Processes of Lactic Acid: Challenges, Solutions, and Future Prospects |
| title_sort | microbial fermentation processes of lactic acid challenges solutions and future prospects |
| topic | lactic acid production microbial fermentation production costs difficulties in production process |
| url | https://www.mdpi.com/2304-8158/12/12/2311 |
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