Phylodynamic analysis in the understanding of the current COVID-19 pandemic and its utility in vaccine and antiviral design and assessment
Over the last decades, the use of phylogenetic methods in the study of emerging infectious diseases has gained considerable traction in public health. Particularly, the integration of phylogenetic analyses with the understanding of the pathogen dynamics at the population level has provided powerful...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-08-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2021.1880254 |
| _version_ | 1797674561096908800 |
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| author | Jaime A. Cardona-Ospina Diana M. Rojas-Gallardo Sandra C. Garzón-Castaño Erika V. Jiménez-Posada Alfonso J. Rodríguez-Morales |
| author_facet | Jaime A. Cardona-Ospina Diana M. Rojas-Gallardo Sandra C. Garzón-Castaño Erika V. Jiménez-Posada Alfonso J. Rodríguez-Morales |
| author_sort | Jaime A. Cardona-Ospina |
| collection | DOAJ |
| description | Over the last decades, the use of phylogenetic methods in the study of emerging infectious diseases has gained considerable traction in public health. Particularly, the integration of phylogenetic analyses with the understanding of the pathogen dynamics at the population level has provided powerful tools for epidemiological surveillance systems. In the same way, the development of statistical methods and theory, as well as improvement of computational efficiency for evolutionary analysis, has expanded the use of these tools for vaccine and antiviral development. Today with the Coronavirus Disease 2019 (COVID-19), this seems to be critical. In this article, we discuss how the application of phylodynamic analysis can improve the understanding of current pandemic dynamics as well as the design, selection, and evaluation of vaccine candidates and antivirals. |
| first_indexed | 2024-03-11T22:00:48Z |
| format | Article |
| id | doaj.art-93bf040076ad4fa594dd0fa3bbe05378 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:00:48Z |
| publishDate | 2021-08-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-93bf040076ad4fa594dd0fa3bbe053782023-09-25T11:13:19ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2021-08-011782437244410.1080/21645515.2021.18802541880254Phylodynamic analysis in the understanding of the current COVID-19 pandemic and its utility in vaccine and antiviral design and assessmentJaime A. Cardona-Ospina0Diana M. Rojas-Gallardo1Sandra C. Garzón-Castaño2Erika V. Jiménez-Posada3Alfonso J. Rodríguez-Morales4Fundación Universitaria Autónoma de Las AméricasFundación Universitaria Autónoma de Las AméricasFundación Universitaria Autónoma de Las AméricasInstituto Para La Investigación en Ciencias Biomédicas - Sci-HelpFundación Universitaria Autónoma de Las AméricasOver the last decades, the use of phylogenetic methods in the study of emerging infectious diseases has gained considerable traction in public health. Particularly, the integration of phylogenetic analyses with the understanding of the pathogen dynamics at the population level has provided powerful tools for epidemiological surveillance systems. In the same way, the development of statistical methods and theory, as well as improvement of computational efficiency for evolutionary analysis, has expanded the use of these tools for vaccine and antiviral development. Today with the Coronavirus Disease 2019 (COVID-19), this seems to be critical. In this article, we discuss how the application of phylodynamic analysis can improve the understanding of current pandemic dynamics as well as the design, selection, and evaluation of vaccine candidates and antivirals.http://dx.doi.org/10.1080/21645515.2021.1880254sars-cov-2covid-19phylodynamicvaccinesantivirals |
| spellingShingle | Jaime A. Cardona-Ospina Diana M. Rojas-Gallardo Sandra C. Garzón-Castaño Erika V. Jiménez-Posada Alfonso J. Rodríguez-Morales Phylodynamic analysis in the understanding of the current COVID-19 pandemic and its utility in vaccine and antiviral design and assessment Human Vaccines & Immunotherapeutics sars-cov-2 covid-19 phylodynamic vaccines antivirals |
| title | Phylodynamic analysis in the understanding of the current COVID-19 pandemic and its utility in vaccine and antiviral design and assessment |
| title_full | Phylodynamic analysis in the understanding of the current COVID-19 pandemic and its utility in vaccine and antiviral design and assessment |
| title_fullStr | Phylodynamic analysis in the understanding of the current COVID-19 pandemic and its utility in vaccine and antiviral design and assessment |
| title_full_unstemmed | Phylodynamic analysis in the understanding of the current COVID-19 pandemic and its utility in vaccine and antiviral design and assessment |
| title_short | Phylodynamic analysis in the understanding of the current COVID-19 pandemic and its utility in vaccine and antiviral design and assessment |
| title_sort | phylodynamic analysis in the understanding of the current covid 19 pandemic and its utility in vaccine and antiviral design and assessment |
| topic | sars-cov-2 covid-19 phylodynamic vaccines antivirals |
| url | http://dx.doi.org/10.1080/21645515.2021.1880254 |
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