Multiple Brain Abscesses of Odontogenic Origin. May Oral Microbiota Affect Their Development? A Review of the Current Literature
In the last few years, the role of oral microbiota in the setting of oral diseases such as caries, periodontal disease, oral cancer and systemic infections, including rheumatoid arthritis, cardiovascular disease and brain abscess (BA), has attracted the attention of physicians and researchers. Appro...
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MDPI AG
2021-04-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/11/8/3316 |
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| author | Nicola Montemurro Paolo Perrini Walter Marani Bipin Chaurasia Massimo Corsalini Antonio Scarano Biagio Rapone |
| author_facet | Nicola Montemurro Paolo Perrini Walter Marani Bipin Chaurasia Massimo Corsalini Antonio Scarano Biagio Rapone |
| author_sort | Nicola Montemurro |
| collection | DOAJ |
| description | In the last few years, the role of oral microbiota in the setting of oral diseases such as caries, periodontal disease, oral cancer and systemic infections, including rheumatoid arthritis, cardiovascular disease and brain abscess (BA), has attracted the attention of physicians and researchers. Approximately 5–7% of all BAs have an odontogenic origin, representing an important pathological systemic condition with a high morbidity and mortality. A systematic search of two databases (Pubmed and Ovid EMBASE) was performed for studies published up to 5 January 2021, reporting multiple BAs attributed to an odontogenic origin. According to PRISMA guidelines, we included a total of 16 papers reporting multiple BAs due to odontogenic infections. The aim of this review is to investigate the treatment modality and the clinical outcome of patients with multiple BAs due to odontogenic infections, as well as to identify the most common pathogens involved in this pathological status and their role, in the oral microbiota, in the onset of oral infections. A multidisciplinary approach is essential in the management of multiple BAs. Further studies are required to understand better the role of microbiota in the development of multiple BAs. |
| first_indexed | 2024-03-10T12:32:59Z |
| format | Article |
| id | doaj.art-93c50f22cc73470792980674b6ce3fd3 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T12:32:59Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-93c50f22cc73470792980674b6ce3fd32023-11-21T14:32:12ZengMDPI AGApplied Sciences2076-34172021-04-01118331610.3390/app11083316Multiple Brain Abscesses of Odontogenic Origin. May Oral Microbiota Affect Their Development? A Review of the Current LiteratureNicola Montemurro0Paolo Perrini1Walter Marani2Bipin Chaurasia3Massimo Corsalini4Antonio Scarano5Biagio Rapone6Department of Neurosurgery, Azienda Ospedaliera Universitaria Pisana (AOUP), 56100 Pisa, ItalyDepartment of Neurosurgery, Azienda Ospedaliera Universitaria Pisana (AOUP), 56100 Pisa, ItalyUnit of Neurosurgery, Mater Dei Hospital, 70121 Bari, ItalyDepartment of Neurosurgery, Bangladesh State Medical University, Dhaka 1205, BangladeshInterdisciplinary Department of Medicine, University of Bari, 70121 Bari, ItalyDepartment of Oral Science, Nano and Biotechnology and CeSi-Met University of Chieti-Pescara, 66100 Chieti, ItalyDepartment of Basic Medical Sciences, Neurosciences and Sense Organs, “Aldo Moro” University of Bari, 70121 Bari, ItalyIn the last few years, the role of oral microbiota in the setting of oral diseases such as caries, periodontal disease, oral cancer and systemic infections, including rheumatoid arthritis, cardiovascular disease and brain abscess (BA), has attracted the attention of physicians and researchers. Approximately 5–7% of all BAs have an odontogenic origin, representing an important pathological systemic condition with a high morbidity and mortality. A systematic search of two databases (Pubmed and Ovid EMBASE) was performed for studies published up to 5 January 2021, reporting multiple BAs attributed to an odontogenic origin. According to PRISMA guidelines, we included a total of 16 papers reporting multiple BAs due to odontogenic infections. The aim of this review is to investigate the treatment modality and the clinical outcome of patients with multiple BAs due to odontogenic infections, as well as to identify the most common pathogens involved in this pathological status and their role, in the oral microbiota, in the onset of oral infections. A multidisciplinary approach is essential in the management of multiple BAs. Further studies are required to understand better the role of microbiota in the development of multiple BAs.https://www.mdpi.com/2076-3417/11/8/3316brain abscessodontogenicdental origincentral nervous system infectiondental infectioncerebral abscess |
| spellingShingle | Nicola Montemurro Paolo Perrini Walter Marani Bipin Chaurasia Massimo Corsalini Antonio Scarano Biagio Rapone Multiple Brain Abscesses of Odontogenic Origin. May Oral Microbiota Affect Their Development? A Review of the Current Literature Applied Sciences brain abscess odontogenic dental origin central nervous system infection dental infection cerebral abscess |
| title | Multiple Brain Abscesses of Odontogenic Origin. May Oral Microbiota Affect Their Development? A Review of the Current Literature |
| title_full | Multiple Brain Abscesses of Odontogenic Origin. May Oral Microbiota Affect Their Development? A Review of the Current Literature |
| title_fullStr | Multiple Brain Abscesses of Odontogenic Origin. May Oral Microbiota Affect Their Development? A Review of the Current Literature |
| title_full_unstemmed | Multiple Brain Abscesses of Odontogenic Origin. May Oral Microbiota Affect Their Development? A Review of the Current Literature |
| title_short | Multiple Brain Abscesses of Odontogenic Origin. May Oral Microbiota Affect Their Development? A Review of the Current Literature |
| title_sort | multiple brain abscesses of odontogenic origin may oral microbiota affect their development a review of the current literature |
| topic | brain abscess odontogenic dental origin central nervous system infection dental infection cerebral abscess |
| url | https://www.mdpi.com/2076-3417/11/8/3316 |
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