Hepatotoxicity-Related Adverse Effects of Proton Pump Inhibitors: A Cross-Sectional Study of Signal Mining and Analysis of the FDA Adverse Event Report System Database

Hepatotoxicity-Related Adverse Effects of Proton Pump Inhibitors: A Cross-Sectional Study of Signal Mining and Analysis of the FDA Adverse Event Report System Database

Background and Objectives: Mounting evidence demonstrates that proton pump inhibitors (PPIs) are associated with a number of adverse effects. However, the literatures about hepatotoxicity-related adverse effects (HRAEs) of PPIs are mostly case reports and a few clinical studies.Methods: We evaluated...

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Bibliographic Details
Main Authors: Yifan Zeng, Ying Dai, Ziye Zhou, Xuben Yu, Dawei Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Medicine
Subjects:
proton pump inhibitors
hepatotoxicity
cholestasis
coma hepatic
hepatitis fulminant
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.648164/full

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