Can One Define the Conductance of Amino Acids?
We studied the electron-transport properties of ten different amino acids and one dimer (di-methionine) using the mechanically controlled break-junction (MCBJ) technique. For methionine and cysteine, additional measurements were performed with the scanning tunneling microscope break-junction (STM-BJ...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-10-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/9/10/580 |
| _version_ | 1819114628941086720 |
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| author | Linda A. Zotti Beatrice Bednarz Juan Hurtado-Gallego Damien Cabosart Gabino Rubio-Bollinger Nicolas Agrait Herre S.J. van der Zant |
| author_facet | Linda A. Zotti Beatrice Bednarz Juan Hurtado-Gallego Damien Cabosart Gabino Rubio-Bollinger Nicolas Agrait Herre S.J. van der Zant |
| author_sort | Linda A. Zotti |
| collection | DOAJ |
| description | We studied the electron-transport properties of ten different amino acids and one dimer (di-methionine) using the mechanically controlled break-junction (MCBJ) technique. For methionine and cysteine, additional measurements were performed with the scanning tunneling microscope break-junction (STM-BJ) technique. By means of a statistical clustering technique, we identified several conductance groups for each of the molecules considered. Ab initio calculations revealed that the observed broad conductance distribution stems from the possibility of various binding geometries which can be formed during stretching combined with a multitude of possible conformational changes. The results suggest that it would be helpful to explore different experimental techniques such as recognition tunneling and conditions to help identify the nature of amino-acid-based junctions even further, for example, with the goal to establish a firm platform for their unambiguous recognition by tunneling break-junction experiments. |
| first_indexed | 2024-12-22T04:48:20Z |
| format | Article |
| id | doaj.art-93c7fe3fe7f046ff82af269313a70e91 |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-12-22T04:48:20Z |
| publishDate | 2019-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-93c7fe3fe7f046ff82af269313a70e912022-12-21T18:38:33ZengMDPI AGBiomolecules2218-273X2019-10-0191058010.3390/biom9100580biom9100580Can One Define the Conductance of Amino Acids?Linda A. Zotti0Beatrice Bednarz1Juan Hurtado-Gallego2Damien Cabosart3Gabino Rubio-Bollinger4Nicolas Agrait5Herre S.J. van der Zant6Departamento de Física Teórica de la Materia Condensada, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, SpainKavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The NetherlandsDepartamento de Física de la Materia Condensada, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, SpainKavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The NetherlandsCondensed Matter Physics Center (IFIMAC), Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, SpainCondensed Matter Physics Center (IFIMAC), Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, SpainKavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The NetherlandsWe studied the electron-transport properties of ten different amino acids and one dimer (di-methionine) using the mechanically controlled break-junction (MCBJ) technique. For methionine and cysteine, additional measurements were performed with the scanning tunneling microscope break-junction (STM-BJ) technique. By means of a statistical clustering technique, we identified several conductance groups for each of the molecules considered. Ab initio calculations revealed that the observed broad conductance distribution stems from the possibility of various binding geometries which can be formed during stretching combined with a multitude of possible conformational changes. The results suggest that it would be helpful to explore different experimental techniques such as recognition tunneling and conditions to help identify the nature of amino-acid-based junctions even further, for example, with the goal to establish a firm platform for their unambiguous recognition by tunneling break-junction experiments.https://www.mdpi.com/2218-273X/9/10/580break junctionsdftnegfamino acidselectron transportbiomolecular electronics |
| spellingShingle | Linda A. Zotti Beatrice Bednarz Juan Hurtado-Gallego Damien Cabosart Gabino Rubio-Bollinger Nicolas Agrait Herre S.J. van der Zant Can One Define the Conductance of Amino Acids? Biomolecules break junctions dft negf amino acids electron transport biomolecular electronics |
| title | Can One Define the Conductance of Amino Acids? |
| title_full | Can One Define the Conductance of Amino Acids? |
| title_fullStr | Can One Define the Conductance of Amino Acids? |
| title_full_unstemmed | Can One Define the Conductance of Amino Acids? |
| title_short | Can One Define the Conductance of Amino Acids? |
| title_sort | can one define the conductance of amino acids |
| topic | break junctions dft negf amino acids electron transport biomolecular electronics |
| url | https://www.mdpi.com/2218-273X/9/10/580 |
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