In Vitro Evaluation of Bioavailability of Se from Daily Food Rations and Dietary Supplements
Bioavailability refers to a fraction of a substance that is potentially absorbed from the gastrointestinal tract and enters the systemic circulation (blood). This term is related to various substances, including minerals, that are present in a complex matrix of food which is consumed every day as na...
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MDPI AG
2023-03-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/6/1511 |
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| author | Piotr Bawiec Jan Sawicki Paulina Łasińska-Pracuta Marcin Czop Ireneusz Sowa Katarzyna Iłowiecka Wojciech Koch |
| author_facet | Piotr Bawiec Jan Sawicki Paulina Łasińska-Pracuta Marcin Czop Ireneusz Sowa Katarzyna Iłowiecka Wojciech Koch |
| author_sort | Piotr Bawiec |
| collection | DOAJ |
| description | Bioavailability refers to a fraction of a substance that is potentially absorbed from the gastrointestinal tract and enters the systemic circulation (blood). This term is related to various substances, including minerals, that are present in a complex matrix of food which is consumed every day as natural products and pharmaceutical preparations, e.g., dietary supplements. The purpose of the study was to assess the bioavailability of Se from selected dietary supplements, with the simultaneous assessment of the effect the diet type (standard, basic and high-residue diets) has on relative bioavailability. The research included a two-stage in vitro model of digestion using cellulose dialysis tubes of the food rations with the addition of dietary supplements. Se was determined using the ICP-OES method. The bioavailability of Se from dietary supplements, in the presence of food matrix, was determined to be within the range of 19.31–66.10%. Sodium selenate was characterized by the highest value of this parameter, followed by organic forms and sodium selenite. The basic diet, characterized by moderate protein and high carbohydrate and fiber contents, positively influenced the bioavailability of Se. The bioavailability of Se was also influenced by the pharmaceutical form of the product—the highest was for tablets, followed by capsules and coated tablets. |
| first_indexed | 2024-03-11T06:04:20Z |
| format | Article |
| id | doaj.art-93c93dc637f04707ba0e7a1e683d9b30 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-11T06:04:20Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-93c93dc637f04707ba0e7a1e683d9b302023-11-17T13:06:48ZengMDPI AGNutrients2072-66432023-03-01156151110.3390/nu15061511In Vitro Evaluation of Bioavailability of Se from Daily Food Rations and Dietary SupplementsPiotr Bawiec0Jan Sawicki1Paulina Łasińska-Pracuta2Marcin Czop3Ireneusz Sowa4Katarzyna Iłowiecka5Wojciech Koch6Department of Food and Nutrition, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, PolandDepartment of Analytical Chemistry, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, PolandDepartment of Food and Nutrition, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, PolandDepartment of Clinical Genetics, Medical University of Lublin, Radziwiłłowska 11 Str., 20-080 Lublin, PolandDepartment of Analytical Chemistry, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, PolandDepartment of Food and Nutrition, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, PolandDepartment of Food and Nutrition, Medical University of Lublin, 4a Chodźki Str., 20-093 Lublin, PolandBioavailability refers to a fraction of a substance that is potentially absorbed from the gastrointestinal tract and enters the systemic circulation (blood). This term is related to various substances, including minerals, that are present in a complex matrix of food which is consumed every day as natural products and pharmaceutical preparations, e.g., dietary supplements. The purpose of the study was to assess the bioavailability of Se from selected dietary supplements, with the simultaneous assessment of the effect the diet type (standard, basic and high-residue diets) has on relative bioavailability. The research included a two-stage in vitro model of digestion using cellulose dialysis tubes of the food rations with the addition of dietary supplements. Se was determined using the ICP-OES method. The bioavailability of Se from dietary supplements, in the presence of food matrix, was determined to be within the range of 19.31–66.10%. Sodium selenate was characterized by the highest value of this parameter, followed by organic forms and sodium selenite. The basic diet, characterized by moderate protein and high carbohydrate and fiber contents, positively influenced the bioavailability of Se. The bioavailability of Se was also influenced by the pharmaceutical form of the product—the highest was for tablets, followed by capsules and coated tablets.https://www.mdpi.com/2072-6643/15/6/1511trace elementsseleniumdietsbioavailabilityICP-OES |
| spellingShingle | Piotr Bawiec Jan Sawicki Paulina Łasińska-Pracuta Marcin Czop Ireneusz Sowa Katarzyna Iłowiecka Wojciech Koch In Vitro Evaluation of Bioavailability of Se from Daily Food Rations and Dietary Supplements Nutrients trace elements selenium diets bioavailability ICP-OES |
| title | In Vitro Evaluation of Bioavailability of Se from Daily Food Rations and Dietary Supplements |
| title_full | In Vitro Evaluation of Bioavailability of Se from Daily Food Rations and Dietary Supplements |
| title_fullStr | In Vitro Evaluation of Bioavailability of Se from Daily Food Rations and Dietary Supplements |
| title_full_unstemmed | In Vitro Evaluation of Bioavailability of Se from Daily Food Rations and Dietary Supplements |
| title_short | In Vitro Evaluation of Bioavailability of Se from Daily Food Rations and Dietary Supplements |
| title_sort | in vitro evaluation of bioavailability of se from daily food rations and dietary supplements |
| topic | trace elements selenium diets bioavailability ICP-OES |
| url | https://www.mdpi.com/2072-6643/15/6/1511 |
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