Spontaneous Confinement of mRNA Molecules at Biomolecular Condensate Boundaries

Spontaneous Confinement of mRNA Molecules at Biomolecular Condensate Boundaries

Cellular biomolecular condensates, termed ribonucleoprotein (RNP) granules, are often enriched in messenger RNA (mRNA) molecules relative to the surrounding cytoplasm. Yet, the spatial localization and diffusion of mRNAs in close proximity to phase separated RNP granules are not well understood. In...

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Bibliographic Details
Main Authors: Rebecca T. Perelman, Andreas Schmidt, Umar Khan, Nils G. Walter
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
membraneless organelles
mRNA
HILO microscopy
liquid–liquid phase separation
biomolecular condensates
RNP granules
Online Access:https://www.mdpi.com/2073-4409/12/18/2250

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