A novel C-terminal degron identified in bacterial aldehyde decarbonylases using directed evolution

A novel C-terminal degron identified in bacterial aldehyde decarbonylases using directed evolution

Abstract Background Aldehyde decarbonylases (ADs), which convert acyl aldehydes into alkanes, supply promising solution for producing alkanes from renewable feedstock. However the instability of ADs impedes their further application. Therefore, the current study aimed to investigate the degradation...

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Bibliographic Details
Main Authors: Yilan Liu, Jinjin Chen, Anna N. Khusnutdinova, Kevin Correia, Patrick Diep, Khorcheska A. Batyrova, Kayla Nemr, Robert Flick, Peter Stogios, Alexander F. Yakunin, Radhakrishnan Mahadevan
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Biotechnology for Biofuels
Subjects:
Alkane
Aldehyde decarbonylase
Directed evolution
Degradation tag
Protease
Online Access:http://link.springer.com/article/10.1186/s13068-020-01753-5

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