The Properties and Domain Requirements for Phase Separation of the Sup35 Prion Protein In Vivo

The Properties and Domain Requirements for Phase Separation of the Sup35 Prion Protein In Vivo

The Sup35 prion protein of budding yeast has been reported to undergo phase separation to form liquid droplets both at low pH in vitro and when energy depletion decreases the intracellular pH in vivo. It also has been shown using purified proteins that this phase separation is driven by the prion do...

Full description

Bibliographic Details
Main Authors: Bryan Grimes, Walter Jacob, Amanda R. Liberman, Nathan Kim, Xiaohong Zhao, Daniel C. Masison, Lois E. Greene
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomolecules
Subjects:
phase separation
biomolecular condensates
yeast prion protein
Sup35
prion domain
Online Access:https://www.mdpi.com/2218-273X/13/9/1370

Internet

https://www.mdpi.com/2218-273X/13/9/1370

Similar Items