MiR-193a regulates chemoresistance of human osteosarcoma cells via repression of IRS2

MiR-193a regulates chemoresistance of human osteosarcoma cells via repression of IRS2

Chemoresistance prevents curative potential of chemotherapy in most cases. MicroRNAs (miRNAs) are key players in regulating chemoresistance in osteosarcoma, which is the most common primary bone cancer. Bisulfite sequencing and quantitative real time PCR analyses showed that miR-193a expression is d...

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Bibliographic Details
Main Authors: Haiyan Wang, Fangfang Zhao, Shanbao Cai, Youguang Pu
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Journal of Bone Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137419300557

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