Localization of Eosinophilic Esophagitis from H&E stained images using multispectral imaging

<p>Abstract</p> <p>This study is an initial investigation on the capability of multispectral imaging to capture subtle spectral information that would enable the automatic delineation between the eosinophilic esophagitis and other eosin stained tissue components, especially the RBC...

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Main Authors: Yagi Yukako, Bautista Pinky A
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Diagnostic Pathology
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author Yagi Yukako
Bautista Pinky A
author_facet Yagi Yukako
Bautista Pinky A
author_sort Yagi Yukako
collection DOAJ
description <p>Abstract</p> <p>This study is an initial investigation on the capability of multispectral imaging to capture subtle spectral information that would enable the automatic delineation between the eosinophilic esophagitis and other eosin stained tissue components, especially the RBCs. In the method, a principal component analysis (PCA) was performed on the spectral transmittance samples of the different tissue components, excluding however the transmittance samples of the eosinophilic esophagitis. From the average spectral error configuration of the eosinophilic esophagitis transmittance samples, i.e. the difference between the actual transmittance and the estimated transmittance using <it>m</it> PC vectors, we indentified two spectral bands by which we can localize the eosinophils. Initial results show the possibility of automatically localizing the eosinophilic esophagitis by utilizing spectral information.</p>
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spelling doaj.art-93d4305ad99c4013a3cf1ab779c144bd2022-12-22T03:12:11ZengBMCDiagnostic Pathology1746-15962011-03-016Suppl 1S210.1186/1746-1596-6-S1-S2Localization of Eosinophilic Esophagitis from H&E stained images using multispectral imagingYagi YukakoBautista Pinky A<p>Abstract</p> <p>This study is an initial investigation on the capability of multispectral imaging to capture subtle spectral information that would enable the automatic delineation between the eosinophilic esophagitis and other eosin stained tissue components, especially the RBCs. In the method, a principal component analysis (PCA) was performed on the spectral transmittance samples of the different tissue components, excluding however the transmittance samples of the eosinophilic esophagitis. From the average spectral error configuration of the eosinophilic esophagitis transmittance samples, i.e. the difference between the actual transmittance and the estimated transmittance using <it>m</it> PC vectors, we indentified two spectral bands by which we can localize the eosinophils. Initial results show the possibility of automatically localizing the eosinophilic esophagitis by utilizing spectral information.</p>
spellingShingle Yagi Yukako
Bautista Pinky A
Localization of Eosinophilic Esophagitis from H&E stained images using multispectral imaging
Diagnostic Pathology
title Localization of Eosinophilic Esophagitis from H&E stained images using multispectral imaging
title_full Localization of Eosinophilic Esophagitis from H&E stained images using multispectral imaging
title_fullStr Localization of Eosinophilic Esophagitis from H&E stained images using multispectral imaging
title_full_unstemmed Localization of Eosinophilic Esophagitis from H&E stained images using multispectral imaging
title_short Localization of Eosinophilic Esophagitis from H&E stained images using multispectral imaging
title_sort localization of eosinophilic esophagitis from h e stained images using multispectral imaging
work_keys_str_mv AT yagiyukako localizationofeosinophilicesophagitisfromhestainedimagesusingmultispectralimaging
AT bautistapinkya localizationofeosinophilicesophagitisfromhestainedimagesusingmultispectralimaging