Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts

Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts

Cancer-associated fibroblasts (CAFs) in the tumor microenvironment perform glycolysis to produce energy, i.e., ATP. Since the origin of CAFs is unidentified, it is not determined whether the intracellular metabolism transitions from oxidative phosphorylation (OXPHOS) to glycolysis when normal tissue...

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Bibliographic Details
Main Authors: Yoshihiro Miyazaki, Nobuhito Mori, Yuka Akagi, Tatsuya Oda, Yasuyuki S. Kida
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
cancer-associated fibroblasts
tumor microenvironment
pancreatic cancer
intracellular metabolism
glycolysis
oxidative phosphorylation
Online Access:https://www.mdpi.com/2072-6694/14/6/1375

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